During the last 25 years, the Department of Performance Physiology (formerly Institute of Physiology and Anatomy) has placed the main feature of the scientific work on the physiological consequences of reduced physical activity. In this context, we have participated in various international bed rest and space experiments. (MIR '92, '97 and '97E; EUROMIR '94 and '95; D2 (STS-55); PEGASE; CNES-MIR '99; ESA-ARMS; STS-107).

A typical methodological challenge in such studies is the prevention of a training effect that overlaps with the adaptation process with very small physiological stimuli. In addition, the performance capacity of the subjects reduced with increasing adaptation to the reduced physical stress. This means that conventional performance tests for athletes need to be modified or replaced with a customized new approach.