DBS - Selected Articles

Selected Publications of the Institute of Biochemistry and Center for Preventive Doping Research concerning Dried Blood Spots in Doping Analysis

Thevis M, Kuuranne T, Thomas A, Geyer H. Do dried blood spots have the potential to support result management processes in routine sports drug testing? - Part 2: Proactive sampling for follow-up investigations concerning atypical or adverse analytical findings. Drug Test Anal. 2021;1–5. 
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Thevis M, Kuuranne T, Dib J, Thomas A, Geyer H.  Do dried blood spots (DBS) have the potential to support result management processes in routine sports drug testing?  Drug Test Anal. 2020;12:704–710.
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Lange T, Thomas A, Walpurgis K, Thevis M. Fully automated dried blood spot sample preparation enables the detection of lower molecular mass peptide and non-peptide doping agents by means of LC-HRMS.  Anal Bioanal Chem. 2020 Apr 16. doi: 10.1007/s00216-020-02634-4. [Epub ahead of print]
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Lange T, Walpurgis K, Thomas A, Geyer H, Thevis M:  Development of two complementary LC-HRMS methods for analyzing sotatercept in dried blood spots for doping controls Bioanalysis. 2019 May;11(10):923-940.

Dib, J. Tretzel, L. Piper, T. Lagojda, A. Kuehne, D. Schänzer, W. Thevis, M:  Screening for adiponectin receptor agonists and their metabolites in urine and dried blood spots. Clim Mass Spec, 2017, 13-20.

Thomas A, Thevis M: Analysis of insulin and insulin analogs from dried blood spots by means of liquid chromatography-high resolution mass spectrometry. Drug Test Anal. 2018 Nov;10(11-12):1761-1768.

L. Tretzel, C. Görgens, H. Geyer, A. Thomas, J. Dib, S. Guddat, V. Pop, W. Schänzer, M. Thevis. Analyses of Meldonium (Mildronate) from Blood, Dried Blood Spots (DBS), and Urine Suggest Drug Incorporation into Erythrocytes. Int J Sports Med. 2016 Jun;37(6):500-2.

Tretzel L, Thomas A, Geyer H, Pop V, Schanzer W, Thevis M: Dried blood spots (DBS) in doping controls: a complementary matrix for improved in- and out-of-competition sports drug testing strategies. Anal. Methods, 2015, 7, 7596–7605.

Tretzel L, Thomas A, Geyer H, Delahaut P, Schänzer W, Thevis M. Determination of Synacthen® in dried blood spots for doping control analysis using liquid chromatography tandem mass spectrometry. Anal Bioanal Chem. 2015 Jun;407(16):4709-20.

Tretzel L, Thomas A, Sköld K, Zeeberg D, Schänzer W, Thevis M: Improvement of the stability of Synacthen® in Dried Blood Spots by means of heat stabilization. In: Schänzer W, Thevis M, Geyer H, Mareck U (eds.) Recent advances in doping analysis (23). Sportverlag Strauß, Köln (2015) 126-129.

Höppner S, Delahaut P, Schänzer W, Thevis M. Mass spectrometric studies on the in vivo metabolism and excretionof SIRT1 activating drugs in rat urine, dried blood spots, and plasmasamples for doping control purposes J Pharm Biomed Anal, 2014, 88, 649-659.

Tretzel L, Thomas A, Geyer H, Gmeiner G, Forsdahl G, Pop V, Schänzer W, Thevis M. Use of dried blood spots in doping control analysis of anabolic steroid esters  J Pharm Biomed Anal, 2014 Aug 5;96:21-30.

Thomas A, Geyer H, Schänzer W, Crone C, Kellmann M, Moehring T, Thevis M Sensitive determination of prohibited drugs in dried blood spots (DBS) for doping controls by means of a benchtop quadrupole/Orbitrap mass spectrometer Anal Bioanal Chem. 2012 May;403(5):1279-89.

Möller I, Thomas A, Geyer H, Schänzer W, Thevis M.  Development and validation of a mass spectrometric detection method of peginesatide in dried blood spots for sports drug testing. Anal Bioanal Chem, 2012 Jul;403(9):2715-24.

A. Thomas, H. Geyer, S. Guddat, W. Schänzer. M Thevis. Dried blood spots (DBS) for doping control analysis Drug Testing and Analysis 2011, 3, 11-12: 806-813.