1 Summary of Major Modifications 10 September 2012 10 September 2012 2013 Prohibited List Summary of Major Modifications and Explanatory Notes SUBSTANCES AND METHODS PROHIBITED AT ALL TIMES (IN- AND OUT-OF-COMPETITION) PROHIBITED SUBSTANCES S0: Non-Approved Substances • It is clarified that veterinary products only refer to substances not approved for human use. S1. Anabolic Agents • The IUPAC names have been reviewed with the assistance of IUPAC and the appropriate changes have been introduced for the following substances : danazol ([1,2]oxazolo[4',5':2,3]pregna-4-en-20-yn-17α-ol) ethylestrenol (19-norpregna-4-en-17α-ol) furazabol (17α-methyl[1,2,5]oxadiazolo[3',4':2,3]-5α- androstan-17β-ol) methasterone (17β-hydroxy-2α,17α-dimethyl-5α- androstan-3-one) prostanozol(17β-[(tetrahydropyran-2-yl)oxy]-1'H- pyrazolo[3,4:2,3]-5α-androstane) tetrahydrogestrinone(17-hydroxy-18a-homo-19-nor-17α- pregna-4,9,11-trien-3-one) trenbolone (17β-hydroxyestr-4,9,11-trien-3-one) prasterone (dehydroepiandrosterone, DHEA, 3β- hydroxyandrost-5-en-17-one). 2 Summary of Major Modifications 10 September 2012 • Etiocholanolone has been added to the S1.b section as an example of testosterone metabolite. The INN will be used if existing; IUPAC nomenclature will also be used when necessary for further clarity; common names will be added where considered helpful. S2. Peptide Hormones, Growth Factors and Related Substances • Insulins have been moved to S4.5.a (Metabolic Modulators) because it is considered a more appropriate category based on their mechanism of action. Other antidiabetic drugs, including exenatide and liraglutide are not prohibited. Platelet-derived preparations (PRP) were previously removed from the List after consideration of the lack of any current evidence concerning the use of these methods for purposes of performance enhancement notwithstanding that these preparations contain growth factors. Despite the presence of some growth factors, current studies on PRP do not demonstrate any potential for performance enhancement beyond a potential therapeutic effect. Note that individual growth factors are still prohibited when given separately as purified substances as described in S.2.5. Intravenous use of PRP is not permitted in accordance with M2. S3. Beta2-agonists: • The permitted delivered (inhaled) dose of formoterol has increased to 54 micrograms over 24 hours with a corresponding increase of the urinary threshold to 40 ng/mL. • For clarity, all optical isomers (d- and l-) where relevant, are prohibited. It should be noted that there are differences worldwide in the labelling of the formoterol content in inhalation devices, and that the List refers to the delivered dose of formoterol and not the metered dose. The delivered dose is the dose that leaves the mouthpiece and is available for inhalation. For example, a Symbicort® Turbuhaler®/Turbohaler® labelled as containing 12 micrograms of formoterol delivers to the patient ~9 micrograms per inhalation. If two inhalations twice a day (i.e. 48 micrograms) are administered, the delivered dose is 36 micrograms, which is the maximum approved daily dose in most countries. In some countries the permitted maximum delivered dose for temporary occasional use for treatment of asthma exacerbations is 54 micrograms over 24 hours. Where formoterol is delivered via an Aerolizer® device, studies have shown that 60-85% of the dose is delivered. WADA is continuing to evaluate other beta-2-agonists in order to establish appropriate urinary threshold levels for these products. Regardless of the dosage permitted, all athletes are encouraged to seek appropriate medical advice to ensure that they are receiving optimal treatment. For more information regarding beta-2-agonists refer to the Medical Information to Assist TUE Committees document on Asthma. 3 Summary of Major Modifications 10 September 2012 S4. Hormone and Metabolic Modulators • Insulins are included under S4.5.a (see S2 above). S5: Diuretics and Other masking agents • “Local application” of felypressin is changed to “Local administration” for clarity. • Morphine is removed from the last paragraph as it is not a substance subject to threshold limits in the List so a TUE would always be required to use in-competition. PROHIBITED METHODS M1. Manipulation of blood and blood components • The title and the body of this section have been changed to encompass all kinds of manipulations of blood and blood components. As a consequence, M2.3 has been deleted, as it is now included in this revised category. M2. Chemical and Physical Manipulation • M2.3 has been deleted as it is now included in the wording of M1. M3. Gene Doping • To enable a more precise definition of Gene Doping, M3.1 has been reworded. SUBSTANCES AND METHODS PROHIBITED IN-COMPETITION S6: Stimulants : • For clarity, it is confirmed that all optical isomers (d- and l-) where relevant, are prohibited. 4 Summary of Major Modifications 10 September 2012 As a reminder some stimulants may be available under several other names, for example “methylhexaneamine”, sometimes presented as dimethylamylamine, pentylamine, geranamine, Forthane, 2- amino-4-methylhexane, geranium root extract or geranium oil. • Another example is methylsynephrine which has been added as a different name for oxilofrine. SUBSTANCES PROHIBITED IN PARTICULAR SPORTS P2. Beta-blockers • Aeronautic (FAI), Boules (CMSB), Bridge (FMB), Ninepin and Tenpin Bowling (FIQ) and Powerboating (UIM) are removed from the list of sports in which beta-blockers are prohibited. WADA continues to re-evaluate the prohibition of beta-blockers in certain sports in conjunction with the concerned federations and other stakeholders. This has led to the removal of five more sports from this section. MONITORING PROGRAM • In order to detect potential patterns of abuse, the following has been added to the Monitoring Program: • In-competition: tapentadol. Summary of Major Modifications and Explanatory Notes

11 September 2013 2014 Prohibited List Summary of Major Modifications and Explanatory Notes SUBSTANCES AND METHODS PROHIBITED AT ALL TIMES (IN- AND OUT-OF- COMPETITION) PROHIBITED SUBSTANCES Use of International Non-proprietary Names (INN) With the assistance of the World Health Organisation, the nomenclature of some substances on the List has been updated to International Non-proprietary Names (INN). For ease of the reviewer the previous name has been included and no substance has been deleted. S1. Anabolic Agents • Changes were made to the definitions of “exogenous” and “endogenous” for purposes of clarification and accuracy. S2. Peptide Hormones, Growth Factors and Related Substances • Releasing factors are prohibited and that is made clear in points S2.2, S2.3 and S2.4. In addition other prohibited growth factors are listed separately. S5. Diuretics and other Masking Agents • Vasopressin V2 antagonists (vaptans) were added as an example of a diuretic subclass. M1. Manipulation of Blood and Blood Components • For the purpose of scientific accuracy, the term allogenic was introduced. SUBSTANCES AND METHODS PROHIBITED IN-COMPETITION S6. Stimulants: • Some drugs that metabolize to amfetamine or methamfetamine have been reclassified because improved analytical techniques permit the identification of the administered drug and corresponding metabolites; MDMA and MDA are reclassified because they are now recognized as less likely to be used as doping agents; cathinone and its analogues (e.g. mephedrone, methedrone, α- pyrrolidinovalerophenone) and trimetazidine have been added as examples to reflect emerging patterns of drug use. SUBSTANCES PROHIBITED IN PARTICULAR SPORTS P1. Alcohol • Changes were made to the wording describing the blood alcohol threshold, in the interest of accuracy. • “Aeronautic” has been replaced by “Air Sports” and “FITA” has been replaced by its new acronym “WA” (World Archery). P2. Beta-blockers • “FITA” has been replaced by its new acronym “WA” (World Archery) MONITORING PROGRAM • In order to detect potential patterns of abuse, mitragynine has been added to the Narcotics class of the Monitoring Program. Summary of Major Modifications and Explanatory Notes

11 September 2013 2014 Prohibited List Summary of Major Modifications and Explanatory Notes SUBSTANCES AND METHODS PROHIBITED AT ALL TIMES (IN- AND OUT-OF- COMPETITION) PROHIBITED SUBSTANCES Use of International Non-proprietary Names (INN) With the assistance of the World Health Organisation, the nomenclature of some substances on the List has been updated to International Non-proprietary Names (INN). For ease of the reviewer the previous name has been included and no substance has been deleted. S1. Anabolic Agents • Changes were made to the definitions of “exogenous” and “endogenous” for purposes of clarification and accuracy. S2. Peptide Hormones, Growth Factors and Related Substances • Releasing factors are prohibited and that is made clear in points S2.2, S2.3 and S2.4. In addition other prohibited growth factors are listed separately. S5. Diuretics and other Masking Agents • Vasopressin V2 antagonists (vaptans) were added as an example of a diuretic subclass. M1. Manipulation of Blood and Blood Components • For the purpose of scientific accuracy, the term allogenic was introduced. SUBSTANCES AND METHODS PROHIBITED IN-COMPETITION S6. Stimulants: • Some drugs that metabolize to amfetamine or methamfetamine have been reclassified because improved analytical techniques permit the identification of the administered drug and corresponding metabolites; MDMA and MDA are reclassified because they are now recognized as less likely to be used as doping agents; cathinone and its analogues (e.g. mephedrone, methedrone, α- pyrrolidinovalerophenone) and trimetazidine have been added as examples to reflect emerging patterns of drug use. SUBSTANCES PROHIBITED IN PARTICULAR SPORTS P1. Alcohol • Changes were made to the wording describing the blood alcohol threshold, in the interest of accuracy. • “Aeronautic” has been replaced by “Air Sports” and “FITA” has been replaced by its new acronym “WA” (World Archery). P2. Beta-blockers • “FITA” has been replaced by its new acronym “WA” (World Archery) MONITORING PROGRAM • In order to detect potential patterns of abuse, mitragynine has been added to the Narcotics class of the Monitoring Program. Summary of Major Modifications and Explanatory Notes

The 2013 Prohibited List 10 September 2012 The World Anti-Doping Code THE 2013 PROHIBITED LIST INTERNATIONAL STANDARD The official text of the Prohibited List shall be maintained by WADA and shall be published in English and French. In the event of any conflict between the English and French versions, the English version shall prevail. This List shall come into effect on 1 January 2013- The 2013 Prohibited List 10 September 2012 2 THE 2013 PROHIBITED LIST WORLD ANTI-DOPING CODE Valid 1 January 2013 In accordance with Article 4.2.2 of the World Anti-Doping Code, all Prohibited Substances shall be considered as “Specified Substances” except Substances in classes S1, S2, S4.4, S4.5, S6.a, and Prohibited Methods M1, M2 and M3. SUBSTANCES AND METHODS PROHIBITED AT ALL TIMES (IN- AND OUT-OF-COMPETITION) PROHIBITED SUBSTANCES S0. NON-APPROVED SUBSTANCES Any pharmacological substance which is not addressed by any of the subsequent sections of the List and with no current approval by any governmental regulatory health authority for human therapeutic use (e.g drugs under pre-clinical or clinical development or discontinued, designer drugs, substances approved only for veterinary use) is prohibited at all times. S1. ANABOLIC AGENTS Anabolic agents are prohibited. 1. Anabolic Androgenic Steroids (AAS) a. Exogenous* AAS, including: 1-androstenediol (5α-androst-1-ene-3β,17β-diol ); 1-androstenedione (5α- androst-1-ene-3,17-dione); bolandiol (estr-4-ene-3β,17β-diol ); bolasterone; boldenone; boldione (androsta-1,4-diene-3,17-dione); calusterone; clostebol; danazol ([1,2]oxazolo[4',5':2,3]pregna-4-en-20-yn-17α-ol); The 2013 Prohibited List 10 September 2012 3 dehydrochlormethyltestosterone (4-chloro-17β-hydroxy-17α-methylandrosta- 1,4-dien-3-one); desoxymethyltestosterone (17α-methyl-5α-androst-2-en- 17β-ol); drostanolone; ethylestrenol (19-norpregna-4-en-17α-ol); fluoxymesterone; formebolone; furazabol (17α- methyl[1,2,5]oxadiazolo[3',4':2,3]-5α-androstan-17β-ol); gestrinone; 4- hydroxytestosterone (4,17β-dihydroxyandrost-4-en-3-one); mestanolone; mesterolone; metenolone; methandienone (17β-hydroxy-17α- methylandrosta-1,4-dien-3-one); methandriol; methasterone (17β-hydroxy- 2α,17α-dimethyl-5α-androstan-3-one); methyldienolone (17β-hydroxy-17α- methylestra-4,9-dien-3-one); methyl-1-testosterone (17β-hydroxy-17α-methyl- 5α-androst-1-en-3-one); methylnortestosterone (17β-hydroxy-17α-methylestr- 4-en-3-one); methyltestosterone; metribolone (methyltrienolone, 17β- hydroxy-17α-methylestra-4,9,11-trien-3-one); mibolerone; nandrolone; 19- norandrostenedione (estr-4-ene-3,17-dione); norboletone; norclostebol; norethandrolone; oxabolone; oxandrolone; oxymesterone; oxymetholone; prostanozol (17β-[(tetrahydropyran-2-yl)oxy]-1'H-pyrazolo[3,4:2,3]-5α- androstane); quinbolone; stanozolol; stenbolone; 1-testosterone (17β- hydroxy-5α-androst-1-en-3-one); tetrahydrogestrinone (17-hydroxy-18a- homo-19-nor-17α-pregna-4,9,11-trien-3-one); trenbolone (17β-hydroxyestr- 4,9,11-trien-3-one); and other substances with a similar chemical structure or similar biological effect(s). b. Endogenous** AAS when administered exogenously: androstenediol (androst-5-ene-3β,17β-diol); androstenedione (androst-4-ene- 3,17-dione); dihydrotestosterone (17β-hydroxy-5α-androstan-3-one); prasterone (dehydroepiandrosterone, DHEA, 3β-hydroxyandrost-5-en-17-one); testosterone; and their metabolites and isomers, including but not limited to: 5α-androstane-3α,17α-diol; 5α-androstane-3α,17β-diol; 5α-androstane- 3β,17α-diol; 5α-androstane-3β,17β-diol; androst-4-ene-3α,17α-diol; androst-4-ene-3α,17β-diol; androst-4-ene-3β,17α-diol; androst-5-ene- 3α,17α-diol; androst-5-ene-3α,17β-diol; androst-5-ene-3β,17α-diol; 4-androstenediol (androst-4-ene-3β,17β-diol); 5-androstenedione (androst-5- ene-3,17-dione); epi-dihydrotestosterone; epitestosterone; etiocholanolone; 3α-hydroxy-5α-androstan-17-one; 3β-hydroxy-5α- androstan-17-one; 7α-hydroxy-DHEA ; 7β-hydroxy-DHEA ; 7-keto-DHEA; 19-norandrosterone; 19-noretiocholanolone. 2. Other Anabolic Agents, including but not limited to: Clenbuterol, selective androgen receptor modulators (SARMs), tibolone, zeranol, zilpaterol. The 2013 Prohibited List 10 September 2012 4 For purposes of this section: * “exogenous” refers to a substance which is not ordinarily capable of being produced by the body naturally. ** “endogenous” refers to a substance which is capable of being produced by the body naturally. S2. PEPTIDE HORMONES, GROWTH FACTORS AND RELATED SUBSTANCES The following substances and their releasing factors are prohibited: 1. Erythropoiesis-Stimulating Agents [e.g. erythropoietin (EPO), darbepoetin (dEPO), hypoxia-inducible factor (HIF) stabilizers, methoxy polyethylene glycol-epoetin beta (CERA), peginesatide (Hematide)]; 2. Chorionic Gonadotrophin (CG) and Luteinizing Hormone (LH) in males; 3. Corticotrophins; 4. Growth Hormone (GH), Insulin-like Growth Factor-1 (IGF-1), Fibroblast Growth Factors (FGFs), Hepatocyte Growth Factor (HGF), Mechano Growth Factors (MGFs), Platelet-Derived Growth Factor (PDGF), Vascular-Endothelial Growth Factor (VEGF) as well as any other growth factor affecting muscle, tendon or ligament protein synthesis/degradation, vascularisation, energy utilization, regenerative capacity or fibre type switching; and other substances with similar chemical structure or similar biological effect(s). S3. BETA-2 AGONISTS All beta-2 agonists, including all optical isomers (e.g. d- and l-) where relevant, are prohibited except inhaled salbutamol (maximum 1600 micrograms over 24 hours), inhaled formoterol (maximum delivered dose 54 micrograms over 24 hours) and salmeterol when taken by inhalation in accordance with the manufacturers’ recommended therapeutic regimen. The presence in urine of salbutamol in excess of 1000 ng/mL or formoterol in excess of 40 ng/mL is presumed not to be an intended therapeutic use of the substance and will be considered as an Adverse Analytical Finding unless the Athlete proves, through a controlled pharmacokinetic study, that the abnormal result was the consequence of the use of the therapeutic inhaled dose up to the maximum indicated above. The 2013 Prohibited List 10 September 2012 5 S4. HORMONE AND METABOLIC MODULATORS The following are prohibited: 1. Aromatase inhibitors including, but not limited to: aminoglutethimide, anastrozole, androsta-1,4,6-triene-3,17-dione (androstatrienedione), 4-androstene-3,6,17 trione (6-oxo), exemestane, formestane, letrozole, testolactone. 2. Selective estrogen receptor modulators (SERMs) including, but not limited to: raloxifene, tamoxifen, toremifene. 3. Other anti-estrogenic substances including, but not limited to: clomiphene, cyclofenil, fulvestrant. 4. Agents modifying myostatin function(s) including, but not limited, to: myostatin inhibitors. 5. Metabolic modulators: a) Insulins b) Peroxisome Proliferator Activated Receptor δ (PPARδ) agonists (e.g. GW 1516), PPARδ-AMP-activated protein kinase (AMPK) axis agonists (e.g. AICAR) S5. DIURETICS AND OTHER MASKING AGENTS Masking agents are prohibited. They include: Diuretics, desmopressin, plasma expanders (e.g. glycerol; intravenous administration of albumin, dextran, hydroxyethyl starch and mannitol), probenecid; and other substances with similar biological effect(s). Local administration of felypressin in dental anaesthesia is not prohibited. Diuretics include: Acetazolamide, amiloride, bumetanide, canrenone, chlorthalidone, etacrynic acid, furosemide, indapamide, metolazone, spironolactone, thiazides (e.g. bendroflumethiazide, chlorothiazide, hydrochlorothiazide), triamterene; and other substances with a similar chemical structure or similar biological effect(s) (except drospirenone, pamabrom and topical dorzolamide and brinzolamide, which are not prohibited). The use In- and Out-of-Competition, as applicable, of any quantity of a substance subject to threshold limits (i.e. formoterol, salbutamol, cathine, ephedrine, methylephedrine and pseudoephedrine) in conjunction with a diuretic or other masking agent requires the deliverance of a specific Therapeutic Use Exemption for that substance in addition to the one granted for the diuretic or other masking agent. The 2013 Prohibited List 10 September 2012 6 PROHIBITED METHODS M1. MANIPULATION OF BLOOD AND BLOOD COMPONENTS The following are prohibited: 1. The administration or reintroduction of any quantity of autologous, homologous or heterologous blood or red blood cell products of any origin into the circulatory system. 2. Artificially enhancing the uptake, transport or delivery of oxygen, including, but not limited to, perfluorochemicals, efaproxiral (RSR13) and modified haemoglobin products (e.g. haemoglobin-based blood substitutes, microencapsulated haemoglobin products), excluding supplemental oxygen. 3. Any form of intravascular manipulation of the blood or blood components by physical or chemical means. M2. CHEMICAL AND PHYSICAL MANIPULATION The following are prohibited: 1. Tampering, or attempting to tamper, in order to alter the integrity and validity of Samples collected during Doping Control. These include but are not limited to urine substitution and/or adulteration (e.g. proteases). 2. Intravenous infusions and/or injections of more than 50 mL per 6 hour period except for those legitimately received in the course of hospital admissions or clinical investigations. M3. GENE DOPING The following, with the potential to enhance sport performance, are prohibited: 1. The transfer of polymers of nucleic acids or nucleic acid analogues; 2. The use of normal or genetically modified cells. The 2013 Prohibited List 10 September 2012 7 SUBSTANCES AND METHODS PROHIBITED IN-COMPETITION In addition to the categories S0 to S5 and M1 to M3 defined above, the following categories are prohibited In-Competition: PROHIBITED SUBSTANCES S6. STIMULANTS All stimulants, including all optical isomers (e.g. d- and l-) where relevant, are prohibited, except imidazole derivatives for topical use and those stimulants included in the 2013 Monitoring Program*. Stimulants include: a: Non-Specified Stimulants: Adrafinil; amfepramone; amiphenazole; amphetamine; amphetaminil; benfluorex; benzphetamine; benzylpiperazine; bromantan; clobenzorex; cocaine; cropropamide; crotetamide; dimethylamphetamine; etilamphetamine; famprofazone; fencamine; fenetylline; fenfluramine; fenproporex; furfenorex; mefenorex; mephentermine; mesocarb; methamphetamine(d-); p-methylamphetamine; methylenedioxyamphetamine; methylenedioxymethamphetamine; modafinil; norfenfluramine; phendimetrazine; phenmetrazine; phentermine; 4-phenylpiracetam (carphedon); prenylamine; prolintane. A stimulant not expressly listed in this section is a Specified Substance. b: Specified Stimulants (examples): Adrenaline**; cathine***; ephedrine****; etamivan; etilefrine; fenbutrazate; fencamfamin; heptaminol; isometheptene; levmetamfetamine; meclofenoxate; methylephedrine****; methylhexaneamine (dimethylpentylamine); methylphenidate; nikethamide; norfenefrine; octopamine; oxilofrine (methylsynephrine); parahydroxyamphetamine; pemoline; pentetrazol; phenpromethamine; propylhexedrine; pseudoephedrine*****; selegiline; sibutramine; strychnine; tuaminoheptane; and other substances with a similar chemical structure or similar biological effect(s). The 2013 Prohibited List 10 September 2012 8 * The following substances included in the 2013 Monitoring Program (bupropion, caffeine, nicotine, phenylephrine, phenylpropanolamine, pipradol, synephrine) are not considered as Prohibited Substances. ** Local administration (e.g. nasal, ophthalmologic) of Adrenaline or co- administration with local anaesthetic agents is not prohibited. *** Cathine is prohibited when its concentration in urine is greater than 5 micrograms per milliliter. **** Each of ephedrine and methylephedrine is prohibited when its concentration in urine is greater than 10 micrograms per milliliter. ***** Pseudoephedrine is prohibited when its concentration in urine is greater than 150 micrograms per milliliter. S7. NARCOTICS The following are prohibited: Buprenorphine, dextromoramide, diamorphine (heroin), fentanyl and its derivatives, hydromorphone, methadone, morphine, oxycodone, oxymorphone, pentazocine, pethidine. S8. CANNABINOIDS Natural (e.g. cannabis, hashish, marijuana) or synthetic delta 9- tetrahydrocannabinol (THC) and cannabimimetics (e.g. “Spice”, JWH018, JWH073, HU-210) are prohibited. S9. GLUCOCORTICOSTEROIDS All glucocorticosteroids are prohibited when administered by oral, intravenous, intramuscular or rectal routes. The 2013 Prohibited List 10 September 2012 9 SUBSTANCES PROHIBITED IN PARTICULAR SPORTS P1. ALCOHOL Alcohol (ethanol) is prohibited In-Competition only, in the following sports. Detection will be conducted by analysis of breath and/or blood. The doping violation threshold (haematological values) is 0.10 g/L. • Aeronautic (FAI) • Archery (FITA) • Automobile (FIA) • Karate (WKF) • Motorcycling (FIM) • Powerboating (UIM) P2. BETA-BLOCKERS Unless otherwise specified, beta-blockers are prohibited In-Competition only, in the following sports. • Archery (FITA) (also prohibited Out-of-Competition) • Automobile (FIA) • Billiards (all disciplines) (WCBS) • Darts (WDF) • Golf (IGF) • Shooting (ISSF, IPC) (also prohibited Out-of-Competition) • Skiing/Snowboarding (FIS) in ski jumping, freestyle aerials/halfpipe and snowboard halfpipe/big air Beta-blockers include, but are not limited to, the following: Acebutolol, alprenolol, atenolol, betaxolol, bisoprolol, bunolol, carteolol, carvedilol, celiprolol, esmolol, labetalol, levobunolol, metipranolol, metoprolol, nadolol, oxprenolol, pindolol, propranolol, sotalol, timolol. THE 2013 PROHIBITED LIST SUBSTANCES AND METHODS PROHIBITED AT ALL TIMES (IN- AND OUT-OF-COMPETITION) 1. UAnabolic Androgenic Steroids (AAS) a. Exogenous* AAS, including: SUBSTANCES AND METHODS PROHIBITED IN-COMPETITION In addition to the categories S0 to S5 and M1 to M3 defined above, the following categories are prohibited In-Competition: US6. STIMULANTS US8. CANNABINOIDS US9. GLUCOCORTICOSTEROIDS All glucocorticosteroids are prohibited when administered by oral, intravenous, intramuscular or rectal routes. UP1. ALCOHOL Aeronautic (FAI) Archery (FITA) Automobile (FIA) Karate (WKF) Motorcycling (FIM) UP2. BETA-BLOCKERS

The 2013 Prohibited List 10 September 2012 The World Anti-Doping Code THE 2013 PROHIBITED LIST INTERNATIONAL STANDARD The official text of the Prohibited List shall be maintained by WADA and shall be published in English and French. In the event of any conflict between the English and French versions, the English version shall prevail. This List shall come into effect on 1 January 2013- The 2013 Prohibited List 10 September 2012 2 THE 2013 PROHIBITED LIST WORLD ANTI-DOPING CODE Valid 1 January 2013 In accordance with Article 4.2.2 of the World Anti-Doping Code, all Prohibited Substances shall be considered as “Specified Substances” except Substances in classes S1, S2, S4.4, S4.5, S6.a, and Prohibited Methods M1, M2 and M3. SUBSTANCES AND METHODS PROHIBITED AT ALL TIMES (IN- AND OUT-OF-COMPETITION) PROHIBITED SUBSTANCES S0. NON-APPROVED SUBSTANCES Any pharmacological substance which is not addressed by any of the subsequent sections of the List and with no current approval by any governmental regulatory health authority for human therapeutic use (e.g drugs under pre-clinical or clinical development or discontinued, designer drugs, substances approved only for veterinary use) is prohibited at all times. S1. ANABOLIC AGENTS Anabolic agents are prohibited. 1. Anabolic Androgenic Steroids (AAS) a. Exogenous* AAS, including: 1-androstenediol (5α-androst-1-ene-3β,17β-diol ); 1-androstenedione (5α- androst-1-ene-3,17-dione); bolandiol (estr-4-ene-3β,17β-diol ); bolasterone; boldenone; boldione (androsta-1,4-diene-3,17-dione); calusterone; clostebol; danazol ([1,2]oxazolo[4',5':2,3]pregna-4-en-20-yn-17α-ol); The 2013 Prohibited List 10 September 2012 3 dehydrochlormethyltestosterone (4-chloro-17β-hydroxy-17α-methylandrosta- 1,4-dien-3-one); desoxymethyltestosterone (17α-methyl-5α-androst-2-en- 17β-ol); drostanolone; ethylestrenol (19-norpregna-4-en-17α-ol); fluoxymesterone; formebolone; furazabol (17α- methyl[1,2,5]oxadiazolo[3',4':2,3]-5α-androstan-17β-ol); gestrinone; 4- hydroxytestosterone (4,17β-dihydroxyandrost-4-en-3-one); mestanolone; mesterolone; metenolone; methandienone (17β-hydroxy-17α- methylandrosta-1,4-dien-3-one); methandriol; methasterone (17β-hydroxy- 2α,17α-dimethyl-5α-androstan-3-one); methyldienolone (17β-hydroxy-17α- methylestra-4,9-dien-3-one); methyl-1-testosterone (17β-hydroxy-17α-methyl- 5α-androst-1-en-3-one); methylnortestosterone (17β-hydroxy-17α-methylestr- 4-en-3-one); methyltestosterone; metribolone (methyltrienolone, 17β- hydroxy-17α-methylestra-4,9,11-trien-3-one); mibolerone; nandrolone; 19- norandrostenedione (estr-4-ene-3,17-dione); norboletone; norclostebol; norethandrolone; oxabolone; oxandrolone; oxymesterone; oxymetholone; prostanozol (17β-[(tetrahydropyran-2-yl)oxy]-1'H-pyrazolo[3,4:2,3]-5α- androstane); quinbolone; stanozolol; stenbolone; 1-testosterone (17β- hydroxy-5α-androst-1-en-3-one); tetrahydrogestrinone (17-hydroxy-18a- homo-19-nor-17α-pregna-4,9,11-trien-3-one); trenbolone (17β-hydroxyestr- 4,9,11-trien-3-one); and other substances with a similar chemical structure or similar biological effect(s). b. Endogenous** AAS when administered exogenously: androstenediol (androst-5-ene-3β,17β-diol); androstenedione (androst-4-ene- 3,17-dione); dihydrotestosterone (17β-hydroxy-5α-androstan-3-one); prasterone (dehydroepiandrosterone, DHEA, 3β-hydroxyandrost-5-en-17-one); testosterone; and their metabolites and isomers, including but not limited to: 5α-androstane-3α,17α-diol; 5α-androstane-3α,17β-diol; 5α-androstane- 3β,17α-diol; 5α-androstane-3β,17β-diol; androst-4-ene-3α,17α-diol; androst-4-ene-3α,17β-diol; androst-4-ene-3β,17α-diol; androst-5-ene- 3α,17α-diol; androst-5-ene-3α,17β-diol; androst-5-ene-3β,17α-diol; 4-androstenediol (androst-4-ene-3β,17β-diol); 5-androstenedione (androst-5- ene-3,17-dione); epi-dihydrotestosterone; epitestosterone; etiocholanolone; 3α-hydroxy-5α-androstan-17-one; 3β-hydroxy-5α- androstan-17-one; 7α-hydroxy-DHEA ; 7β-hydroxy-DHEA ; 7-keto-DHEA; 19-norandrosterone; 19-noretiocholanolone. 2. Other Anabolic Agents, including but not limited to: Clenbuterol, selective androgen receptor modulators (SARMs), tibolone, zeranol, zilpaterol. The 2013 Prohibited List 10 September 2012 4 For purposes of this section: * “exogenous” refers to a substance which is not ordinarily capable of being produced by the body naturally. ** “endogenous” refers to a substance which is capable of being produced by the body naturally. S2. PEPTIDE HORMONES, GROWTH FACTORS AND RELATED SUBSTANCES The following substances and their releasing factors are prohibited: 1. Erythropoiesis-Stimulating Agents [e.g. erythropoietin (EPO), darbepoetin (dEPO), hypoxia-inducible factor (HIF) stabilizers, methoxy polyethylene glycol-epoetin beta (CERA), peginesatide (Hematide)]; 2. Chorionic Gonadotrophin (CG) and Luteinizing Hormone (LH) in males; 3. Corticotrophins; 4. Growth Hormone (GH), Insulin-like Growth Factor-1 (IGF-1), Fibroblast Growth Factors (FGFs), Hepatocyte Growth Factor (HGF), Mechano Growth Factors (MGFs), Platelet-Derived Growth Factor (PDGF), Vascular-Endothelial Growth Factor (VEGF) as well as any other growth factor affecting muscle, tendon or ligament protein synthesis/degradation, vascularisation, energy utilization, regenerative capacity or fibre type switching; and other substances with similar chemical structure or similar biological effect(s). S3. BETA-2 AGONISTS All beta-2 agonists, including all optical isomers (e.g. d- and l-) where relevant, are prohibited except inhaled salbutamol (maximum 1600 micrograms over 24 hours), inhaled formoterol (maximum delivered dose 54 micrograms over 24 hours) and salmeterol when taken by inhalation in accordance with the manufacturers’ recommended therapeutic regimen. The presence in urine of salbutamol in excess of 1000 ng/mL or formoterol in excess of 40 ng/mL is presumed not to be an intended therapeutic use of the substance and will be considered as an Adverse Analytical Finding unless the Athlete proves, through a controlled pharmacokinetic study, that the abnormal result was the consequence of the use of the therapeutic inhaled dose up to the maximum indicated above. The 2013 Prohibited List 10 September 2012 5 S4. HORMONE AND METABOLIC MODULATORS The following are prohibited: 1. Aromatase inhibitors including, but not limited to: aminoglutethimide, anastrozole, androsta-1,4,6-triene-3,17-dione (androstatrienedione), 4-androstene-3,6,17 trione (6-oxo), exemestane, formestane, letrozole, testolactone. 2. Selective estrogen receptor modulators (SERMs) including, but not limited to: raloxifene, tamoxifen, toremifene. 3. Other anti-estrogenic substances including, but not limited to: clomiphene, cyclofenil, fulvestrant. 4. Agents modifying myostatin function(s) including, but not limited, to: myostatin inhibitors. 5. Metabolic modulators: a) Insulins b) Peroxisome Proliferator Activated Receptor δ (PPARδ) agonists (e.g. GW 1516), PPARδ-AMP-activated protein kinase (AMPK) axis agonists (e.g. AICAR) S5. DIURETICS AND OTHER MASKING AGENTS Masking agents are prohibited. They include: Diuretics, desmopressin, plasma expanders (e.g. glycerol; intravenous administration of albumin, dextran, hydroxyethyl starch and mannitol), probenecid; and other substances with similar biological effect(s). Local administration of felypressin in dental anaesthesia is not prohibited. Diuretics include: Acetazolamide, amiloride, bumetanide, canrenone, chlorthalidone, etacrynic acid, furosemide, indapamide, metolazone, spironolactone, thiazides (e.g. bendroflumethiazide, chlorothiazide, hydrochlorothiazide), triamterene; and other substances with a similar chemical structure or similar biological effect(s) (except drospirenone, pamabrom and topical dorzolamide and brinzolamide, which are not prohibited). The use In- and Out-of-Competition, as applicable, of any quantity of a substance subject to threshold limits (i.e. formoterol, salbutamol, cathine, ephedrine, methylephedrine and pseudoephedrine) in conjunction with a diuretic or other masking agent requires the deliverance of a specific Therapeutic Use Exemption for that substance in addition to the one granted for the diuretic or other masking agent. The 2013 Prohibited List 10 September 2012 6 PROHIBITED METHODS M1. MANIPULATION OF BLOOD AND BLOOD COMPONENTS The following are prohibited: 1. The administration or reintroduction of any quantity of autologous, homologous or heterologous blood or red blood cell products of any origin into the circulatory system. 2. Artificially enhancing the uptake, transport or delivery of oxygen, including, but not limited to, perfluorochemicals, efaproxiral (RSR13) and modified haemoglobin products (e.g. haemoglobin-based blood substitutes, microencapsulated haemoglobin products), excluding supplemental oxygen. 3. Any form of intravascular manipulation of the blood or blood components by physical or chemical means. M2. CHEMICAL AND PHYSICAL MANIPULATION The following are prohibited: 1. Tampering, or attempting to tamper, in order to alter the integrity and validity of Samples collected during Doping Control. These include but are not limited to urine substitution and/or adulteration (e.g. proteases). 2. Intravenous infusions and/or injections of more than 50 mL per 6 hour period except for those legitimately received in the course of hospital admissions or clinical investigations. M3. GENE DOPING The following, with the potential to enhance sport performance, are prohibited: 1. The transfer of polymers of nucleic acids or nucleic acid analogues; 2. The use of normal or genetically modified cells. The 2013 Prohibited List 10 September 2012 7 SUBSTANCES AND METHODS PROHIBITED IN-COMPETITION In addition to the categories S0 to S5 and M1 to M3 defined above, the following categories are prohibited In-Competition: PROHIBITED SUBSTANCES S6. STIMULANTS All stimulants, including all optical isomers (e.g. d- and l-) where relevant, are prohibited, except imidazole derivatives for topical use and those stimulants included in the 2013 Monitoring Program*. Stimulants include: a: Non-Specified Stimulants: Adrafinil; amfepramone; amiphenazole; amphetamine; amphetaminil; benfluorex; benzphetamine; benzylpiperazine; bromantan; clobenzorex; cocaine; cropropamide; crotetamide; dimethylamphetamine; etilamphetamine; famprofazone; fencamine; fenetylline; fenfluramine; fenproporex; furfenorex; mefenorex; mephentermine; mesocarb; methamphetamine(d-); p-methylamphetamine; methylenedioxyamphetamine; methylenedioxymethamphetamine; modafinil; norfenfluramine; phendimetrazine; phenmetrazine; phentermine; 4-phenylpiracetam (carphedon); prenylamine; prolintane. A stimulant not expressly listed in this section is a Specified Substance. b: Specified Stimulants (examples): Adrenaline**; cathine***; ephedrine****; etamivan; etilefrine; fenbutrazate; fencamfamin; heptaminol; isometheptene; levmetamfetamine; meclofenoxate; methylephedrine****; methylhexaneamine (dimethylpentylamine); methylphenidate; nikethamide; norfenefrine; octopamine; oxilofrine (methylsynephrine); parahydroxyamphetamine; pemoline; pentetrazol; phenpromethamine; propylhexedrine; pseudoephedrine*****; selegiline; sibutramine; strychnine; tuaminoheptane; and other substances with a similar chemical structure or similar biological effect(s). The 2013 Prohibited List 10 September 2012 8 * The following substances included in the 2013 Monitoring Program (bupropion, caffeine, nicotine, phenylephrine, phenylpropanolamine, pipradol, synephrine) are not considered as Prohibited Substances. ** Local administration (e.g. nasal, ophthalmologic) of Adrenaline or co- administration with local anaesthetic agents is not prohibited. *** Cathine is prohibited when its concentration in urine is greater than 5 micrograms per milliliter. **** Each of ephedrine and methylephedrine is prohibited when its concentration in urine is greater than 10 micrograms per milliliter. ***** Pseudoephedrine is prohibited when its concentration in urine is greater than 150 micrograms per milliliter. S7. NARCOTICS The following are prohibited: Buprenorphine, dextromoramide, diamorphine (heroin), fentanyl and its derivatives, hydromorphone, methadone, morphine, oxycodone, oxymorphone, pentazocine, pethidine. S8. CANNABINOIDS Natural (e.g. cannabis, hashish, marijuana) or synthetic delta 9- tetrahydrocannabinol (THC) and cannabimimetics (e.g. “Spice”, JWH018, JWH073, HU-210) are prohibited. S9. GLUCOCORTICOSTEROIDS All glucocorticosteroids are prohibited when administered by oral, intravenous, intramuscular or rectal routes. The 2013 Prohibited List 10 September 2012 9 SUBSTANCES PROHIBITED IN PARTICULAR SPORTS P1. ALCOHOL Alcohol (ethanol) is prohibited In-Competition only, in the following sports. Detection will be conducted by analysis of breath and/or blood. The doping violation threshold (haematological values) is 0.10 g/L. • Aeronautic (FAI) • Archery (FITA) • Automobile (FIA) • Karate (WKF) • Motorcycling (FIM) • Powerboating (UIM) P2. BETA-BLOCKERS Unless otherwise specified, beta-blockers are prohibited In-Competition only, in the following sports. • Archery (FITA) (also prohibited Out-of-Competition) • Automobile (FIA) • Billiards (all disciplines) (WCBS) • Darts (WDF) • Golf (IGF) • Shooting (ISSF, IPC) (also prohibited Out-of-Competition) • Skiing/Snowboarding (FIS) in ski jumping, freestyle aerials/halfpipe and snowboard halfpipe/big air Beta-blockers include, but are not limited to, the following: Acebutolol, alprenolol, atenolol, betaxolol, bisoprolol, bunolol, carteolol, carvedilol, celiprolol, esmolol, labetalol, levobunolol, metipranolol, metoprolol, nadolol, oxprenolol, pindolol, propranolol, sotalol, timolol. THE 2013 PROHIBITED LIST SUBSTANCES AND METHODS PROHIBITED AT ALL TIMES (IN- AND OUT-OF-COMPETITION) 1. UAnabolic Androgenic Steroids (AAS) a. Exogenous* AAS, including: SUBSTANCES AND METHODS PROHIBITED IN-COMPETITION In addition to the categories S0 to S5 and M1 to M3 defined above, the following categories are prohibited In-Competition: US6. STIMULANTS US8. CANNABINOIDS US9. GLUCOCORTICOSTEROIDS All glucocorticosteroids are prohibited when administered by oral, intravenous, intramuscular or rectal routes. UP1. ALCOHOL Aeronautic (FAI) Archery (FITA) Automobile (FIA) Karate (WKF) Motorcycling (FIM) UP2. BETA-BLOCKERS

The 2014 Prohibited List 11 September 2013 The World Anti-Doping Code THE 2014 PROHIBITED LIST INTERNATIONAL STANDARD The official text of the Prohibited List shall be maintained by WADA and shall be published in English and French. In the event of any conflict between the English and French versions, the English version shall prevail. This List shall come into effect on 1 January 2014 The 2014 Prohibited List 11 September 2013 2 THE 2014 PROHIBITED LIST WORLD ANTI-DOPING CODE Valid 1 January 2014 In accordance with Article 4.2.2 of the World Anti-Doping Code, all Prohibited Substances shall be considered as “Specified Substances” except Substances in classes S1, S2, S4.4, S4.5, S6.a, and Prohibited Methods M1, M2 and M3. SUBSTANCES AND METHODS PROHIBITED AT ALL TIMES (IN- AND OUT-OF-COMPETITION) PROHIBITED SUBSTANCES S0. NON-APPROVED SUBSTANCES Any pharmacological substance which is not addressed by any of the subsequent sections of the List and with no current approval by any governmental regulatory health authority for human therapeutic use (e.g drugs under pre-clinical or clinical development or discontinued, designer drugs, substances approved only for veterinary use) is prohibited at all times. S1. ANABOLIC AGENTS Anabolic agents are prohibited. 1. Anabolic Androgenic Steroids (AAS) a. Exogenous* AAS, including: 1-androstenediol (5α-androst-1-ene-3β,17β-diol ); 1-androstenedione (5α- androst-1-ene-3,17-dione); bolandiol (estr-4-ene-3β,17β-diol ); bolasterone; boldenone; boldione (androsta-1,4-diene-3,17-dione); calusterone; clostebol; danazol ([1,2]oxazolo[4',5':2,3]pregna-4-en-20-yn-17α-ol); The 2014 Prohibited List 11 September 2013 3 dehydrochlormethyltestosterone (4-chloro-17β-hydroxy-17α-methylandrosta- 1,4-dien-3-one); desoxymethyltestosterone (17α-methyl-5α-androst-2-en- 17β-ol); drostanolone; ethylestrenol (19-norpregna-4-en-17α-ol); fluoxymesterone; formebolone; furazabol (17α- methyl[1,2,5]oxadiazolo[3',4':2,3]-5α-androstan-17β-ol); gestrinone; 4- hydroxytestosterone (4,17β-dihydroxyandrost-4-en-3-one); mestanolone; mesterolone; metandienone (17β-hydroxy-17α-methylandrosta-1,4-dien-3- one); metenolone; methandriol; methasterone (17β-hydroxy-2α,17α- dimethyl-5α-androstan-3-one); methyldienolone (17β-hydroxy-17α- methylestra-4,9-dien-3-one); methyl-1-testosterone (17β-hydroxy-17α-methyl- 5α-androst-1-en-3-one); methylnortestosterone (17β-hydroxy-17α-methylestr- 4-en-3-one); methyltestosterone; metribolone (methyltrienolone, 17β- hydroxy-17α-methylestra-4,9,11-trien-3-one); mibolerone; nandrolone; 19- norandrostenedione (estr-4-ene-3,17-dione); norboletone; norclostebol; norethandrolone; oxabolone; oxandrolone; oxymesterone; oxymetholone; prostanozol (17β-[(tetrahydropyran-2-yl)oxy]-1'H-pyrazolo[3,4:2,3]-5α- androstane); quinbolone; stanozolol; stenbolone; 1-testosterone (17β- hydroxy-5α-androst-1-en-3-one); tetrahydrogestrinone (17-hydroxy-18a- homo-19-nor-17α-pregna-4,9,11-trien-3-one); trenbolone (17β-hydroxyestr- 4,9,11-trien-3-one); and other substances with a similar chemical structure or similar biological effect(s). b. Endogenous** AAS when administered exogenously: androstenediol (androst-5-ene-3β,17β-diol); androstenedione (androst-4-ene- 3,17-dione); dihydrotestosterone (17β-hydroxy-5α-androstan-3-one); prasterone (dehydroepiandrosterone, DHEA, 3β-hydroxyandrost-5-en-17-one); testosterone; and their metabolites and isomers, including but not limited to: 5α-androstane-3α,17α-diol; 5α-androstane-3α,17β-diol; 5α-androstane- 3β,17α-diol; 5α-androstane-3β,17β-diol; androst-4-ene-3α,17α-diol; androst-4-ene-3α,17β-diol; androst-4-ene-3β,17α-diol; androst-5-ene- 3α,17α-diol; androst-5-ene-3α,17β-diol; androst-5-ene-3β,17α-diol; 4-androstenediol (androst-4-ene-3β,17β-diol); 5-androstenedione (androst-5- ene-3,17-dione); epi-dihydrotestosterone; epitestosterone; etiocholanolone; 3α-hydroxy-5α-androstan-17-one; 3β-hydroxy-5α- androstan-17-one; 7α-hydroxy-DHEA ; 7β-hydroxy-DHEA ; 7-keto-DHEA; 19-norandrosterone; 19-noretiocholanolone. 2. Other Anabolic Agents, including but not limited to: Clenbuterol, selective androgen receptor modulators (SARMs), tibolone, zeranol, zilpaterol. The 2014 Prohibited List 11 September 2013 4 For purposes of this section: * “exogenous” refers to a substance which is not ordinarily produced by the body naturally. ** “endogenous” refers to a substance which is ordinarily produced by the body naturally. S2. PEPTIDE HORMONES, GROWTH FACTORS AND RELATED SUBSTANCES The following substances, and other substances with similar chemical structure or similar biological effect(s), are prohibited: 1. Erythropoiesis-Stimulating Agents [e.g. erythropoietin (EPO), darbepoetin (dEPO), hypoxia-inducible factor (HIF) stabilizers, methoxy polyethylene glycol-epoetin beta (CERA), peginesatide (Hematide)]; 2. Chorionic Gonadotrophin (CG) and Luteinizing Hormone (LH) and their releasing factors, in males; 3. Corticotrophins and their releasing factors; 4. Growth Hormone (GH) and its releasing factors and Insulin-like Growth Factor-1 (IGF-1). In addition, the following growth factors are prohibited Fibroblast Growth Factors (FGFs), Hepatocyte Growth Factor (HGF), Mechano Growth Factors (MGFs), Platelet-Derived Growth Factor (PDGF), Vascular-Endothelial Growth Factor (VEGF) as well as any other growth factor affecting muscle, tendon or ligament protein synthesis/degradation, vascularisation, energy utilization, regenerative capacity or fibre type switching; and other substances with similar chemical structure or similar biological effect(s). S3. BETA-2 AGONISTS All beta-2 agonists, including all optical isomers (e.g. d- and l-) where relevant, are prohibited except inhaled salbutamol (maximum 1600 micrograms over 24 hours), inhaled formoterol (maximum delivered dose 54 micrograms over 24 hours) and salmeterol when taken by inhalation in accordance with the manufacturers’ recommended therapeutic regimen. The 2014 Prohibited List 11 September 2013 5 The presence in urine of salbutamol in excess of 1000 ng/mL or formoterol in excess of 40 ng/mL is presumed not to be an intended therapeutic use of the substance and will be considered as an Adverse Analytical Finding unless the Athlete proves, through a controlled pharmacokinetic study, that the abnormal result was the consequence of the use of the therapeutic inhaled dose up to the maximum indicated above. S4. HORMONE AND METABOLIC MODULATORS The following are prohibited: 1. Aromatase inhibitors including, but not limited to: aminoglutethimide, anastrozole, androsta-1,4,6-triene-3,17-dione (androstatrienedione), 4-androstene-3,6,17 trione (6-oxo), exemestane, formestane, letrozole, testolactone. 2. Selective estrogen receptor modulators (SERMs) including, but not limited to: raloxifene, tamoxifen, toremifene. 3. Other anti-estrogenic substances including, but not limited to: clomiphene, cyclofenil, fulvestrant. 4. Agents modifying myostatin function(s) including, but not limited, to: myostatin inhibitors. 5. Metabolic modulators: a) Insulins b) Peroxisome Proliferator Activated Receptor δ (PPARδ) agonists (e.g. GW 1516), PPARδ-AMP-activated protein kinase (AMPK) axis agonists (e.g. AICAR) S5. DIURETICS AND OTHER MASKING AGENTS Masking agents are prohibited. They include: Diuretics, desmopressin, plasma expanders (e.g. glycerol; intravenous administration of albumin, dextran, hydroxyethyl starch and mannitol), probenecid; and other substances with similar biological effect(s). Local administration of felypressin in dental anaesthesia is not prohibited. Diuretics include: Acetazolamide, amiloride, bumetanide, canrenone, chlortalidone, etacrynic acid, furosemide, indapamide, metolazone, spironolactone, thiazides (e.g. bendroflumethiazide, chlorothiazide, hydrochlorothiazide), triamterene, vaptans (e.g. tolvaptan); and other substances with a similar The 2014 Prohibited List 11 September 2013 6 chemical structure or similar biological effect(s) (except drospirenone, pamabrom and topical dorzolamide and brinzolamide, which are not prohibited). The use In- and Out-of-Competition, as applicable, of any quantity of a substance subject to threshold limits (i.e. formoterol, salbutamol, cathine, ephedrine, methylephedrine and pseudoephedrine) in conjunction with a diuretic or other masking agent requires the deliverance of a specific Therapeutic Use Exemption for that substance in addition to the one granted for the diuretic or other masking agent. The 2014 Prohibited List 11 September 2013 7 PROHIBITED METHODS M1. MANIPULATION OF BLOOD AND BLOOD COMPONENTS The following are prohibited: 1. The administration or reintroduction of any quantity of autologous, allogenic (homologous) or heterologous blood or red blood cell products of any origin into the circulatory system. 2. Artificially enhancing the uptake, transport or delivery of oxygen, including, but not limited to, perfluorochemicals, efaproxiral (RSR13) and modified haemoglobin products (e.g. haemoglobin-based blood substitutes, microencapsulated haemoglobin products), excluding supplemental oxygen. 3. Any form of intravascular manipulation of the blood or blood components by physical or chemical means. M2. CHEMICAL AND PHYSICAL MANIPULATION The following are prohibited: 1. Tampering, or attempting to tamper, in order to alter the integrity and validity of Samples collected during Doping Control. These include but are not limited to urine substitution and/or adulteration (e.g. proteases). 2. Intravenous infusions and/or injections of more than 50 mL per 6 hour period except for those legitimately received in the course of hospital admissions or clinical investigations. M3. GENE DOPING The following, with the potential to enhance sport performance, are prohibited: 1. The transfer of polymers of nucleic acids or nucleic acid analogues; 2. The use of normal or genetically modified cells. The 2014 Prohibited List 11 September 2013 8 SUBSTANCES AND METHODS PROHIBITED IN-COMPETITION In addition to the categories S0 to S5 and M1 to M3 defined above, the following categories are prohibited In-Competition: PROHIBITED SUBSTANCES S6. STIMULANTS All stimulants, including all optical isomers (e.g. d- and l-) where relevant, are prohibited, except imidazole derivatives for topical use and those stimulants included in the 2014 Monitoring Program*. Stimulants include: a: Non-Specified Stimulants: Adrafinil; amfepramone; amfetamine; amfetaminil; amiphenazole; benfluorex; benzylpiperazine; bromantan; clobenzorex; cocaine; cropropamide; crotetamide; fencamine; fenetylline; fenfluramine; fenproporex; fonturacetam [4-phenylpiracetam (carphedon)]; furfenorex; mefenorex; mephentermine; mesocarb; metamfetamine(d-); p-methylamphetamine; modafinil; norfenfluramine; phendimetrazine; phenmetrazine; phentermine; prenylamine; prolintane. A stimulant not expressly listed in this section is a Specified Substance. b: Specified Stimulants (examples): Benzfetamine; cathine**; cathinone and its analogues (e.g. mephedrone, methedrone, α- pyrrolidinovalerophenone); dimethylamphetamine; ephedrine***; epinephrine**** (adrenaline); etamivan; etilamfetamine; etilefrine; famprofazone; fenbutrazate; fencamfamin; heptaminol; hydroxyamfetamine (parahydroamphetamine); isometheptene; levmetamfetamine; meclofenoxate; methylenedioxymethamphetamine; methylephedrine***; methylhexaneamine (dimethylpentylamine); methylphenidate; nikethamide; norfenefrine; octopamine; oxilofrine (methylsynephrine); pemoline; pentetrazol; phenpromethamine; propylhexedrine; pseudoephedrine*****; selegiline; sibutramine; strychnine; tenamfetamine (methylenedioxyamphetamine); trimetazidine; tuaminoheptane; and other substances with a similar chemical structure or similar biological effect(s). The 2014 Prohibited List 11 September 2013 9 * The following substances included in the 2014 Monitoring Program (bupropion, caffeine, nicotine, phenylephrine, phenylpropanolamine, pipradol, synephrine) are not considered as Prohibited Substances. ** Cathine is prohibited when its concentration in urine is greater than 5 micrograms per milliliter. *** Each of ephedrine and methylephedrine is prohibited when its concentration in urine is greater than 10 micrograms per milliliter. **** Local administration (e.g. nasal, ophthalmologic) of epinephrine (adrenaline) or co-administration with local anaesthetic agents is not prohibited. ***** Pseudoephedrine is prohibited when its concentration in urine is greater than 150 micrograms per milliliter. S7. NARCOTICS The following are prohibited: Buprenorphine, dextromoramide, diamorphine (heroin), fentanyl and its derivatives, hydromorphone, methadone, morphine, oxycodone, oxymorphone, pentazocine, pethidine. S8. CANNABINOIDS Natural (e.g. cannabis, hashish, marijuana) or synthetic delta 9- tetrahydrocannabinol (THC) and cannabimimetics (e.g. “Spice”, JWH018, JWH073, HU-210) are prohibited. S9. GLUCOCORTICOSTEROIDS All glucocorticosteroids are prohibited when administered by oral, intravenous, intramuscular or rectal routes. The 2014 Prohibited List 11 September 2013 10 SUBSTANCES PROHIBITED IN PARTICULAR SPORTS P1. ALCOHOL Alcohol (ethanol) is prohibited In-Competition only, in the following sports. Detection will be conducted by analysis of breath and/or blood. The doping violation threshold is equivalent to a blood alcohol concentration of 0.10 g/L. • Air Sports (FAI) • Archery (WA) • Automobile (FIA) • Karate (WKF) • Motorcycling (FIM) • Powerboating (UIM) P2. BETA-BLOCKERS Unless otherwise specified, beta-blockers are prohibited In-Competition only, in the following sports. • Archery (WA) (also prohibited Out-of-Competition) • Automobile (FIA) • Billiards (all disciplines) (WCBS) • Darts (WDF) • Golf (IGF) • Shooting (ISSF, IPC) (also prohibited Out-of-Competition) • Skiing/Snowboarding (FIS) in ski jumping, freestyle aerials/halfpipe and snowboard halfpipe/big air Beta-blockers include, but are not limited to, the following: Acebutolol, alprenolol, atenolol, betaxolol, bisoprolol, bunolol, carteolol, carvedilol, celiprolol, esmolol, labetalol, levobunolol, metipranolol, metoprolol, nadolol, oxprenolol, pindolol, propranolol, sotalol, timolol. THE 2014 PROHIBITED LIST SUBSTANCES AND METHODS PROHIBITED AT ALL TIMES (IN- AND OUT-OF-COMPETITION) 1. UAnabolic Androgenic Steroids (AAS) a. Exogenous* AAS, including: SUBSTANCES AND METHODS PROHIBITED IN-COMPETITION In addition to the categories S0 to S5 and M1 to M3 defined above, the following categories are prohibited In-Competition: US6. STIMULANTS US8. CANNABINOIDS US9. GLUCOCORTICOSTEROIDS All glucocorticosteroids are prohibited when administered by oral, intravenous, intramuscular or rectal routes. UP1. ALCOHOL Air Sports (FAI) Archery (WA) Automobile (FIA) Karate (WKF) Motorcycling (FIM) UP2. BETA-BLOCKERS

The 2014 Prohibited List 11 September 2013 The World Anti-Doping Code THE 2014 PROHIBITED LIST INTERNATIONAL STANDARD The official text of the Prohibited List shall be maintained by WADA and shall be published in English and French. In the event of any conflict between the English and French versions, the English version shall prevail. This List shall come into effect on 1 January 2014 The 2014 Prohibited List 11 September 2013 2 THE 2014 PROHIBITED LIST WORLD ANTI-DOPING CODE Valid 1 January 2014 In accordance with Article 4.2.2 of the World Anti-Doping Code, all Prohibited Substances shall be considered as “Specified Substances” except Substances in classes S1, S2, S4.4, S4.5, S6.a, and Prohibited Methods M1, M2 and M3. SUBSTANCES AND METHODS PROHIBITED AT ALL TIMES (IN- AND OUT-OF-COMPETITION) PROHIBITED SUBSTANCES S0. NON-APPROVED SUBSTANCES Any pharmacological substance which is not addressed by any of the subsequent sections of the List and with no current approval by any governmental regulatory health authority for human therapeutic use (e.g drugs under pre-clinical or clinical development or discontinued, designer drugs, substances approved only for veterinary use) is prohibited at all times. S1. ANABOLIC AGENTS Anabolic agents are prohibited. 1. Anabolic Androgenic Steroids (AAS) a. Exogenous* AAS, including: 1-androstenediol (5α-androst-1-ene-3β,17β-diol ); 1-androstenedione (5α- androst-1-ene-3,17-dione); bolandiol (estr-4-ene-3β,17β-diol ); bolasterone; boldenone; boldione (androsta-1,4-diene-3,17-dione); calusterone; clostebol; danazol ([1,2]oxazolo[4',5':2,3]pregna-4-en-20-yn-17α-ol); The 2014 Prohibited List 11 September 2013 3 dehydrochlormethyltestosterone (4-chloro-17β-hydroxy-17α-methylandrosta- 1,4-dien-3-one); desoxymethyltestosterone (17α-methyl-5α-androst-2-en- 17β-ol); drostanolone; ethylestrenol (19-norpregna-4-en-17α-ol); fluoxymesterone; formebolone; furazabol (17α- methyl[1,2,5]oxadiazolo[3',4':2,3]-5α-androstan-17β-ol); gestrinone; 4- hydroxytestosterone (4,17β-dihydroxyandrost-4-en-3-one); mestanolone; mesterolone; metandienone (17β-hydroxy-17α-methylandrosta-1,4-dien-3- one); metenolone; methandriol; methasterone (17β-hydroxy-2α,17α- dimethyl-5α-androstan-3-one); methyldienolone (17β-hydroxy-17α- methylestra-4,9-dien-3-one); methyl-1-testosterone (17β-hydroxy-17α-methyl- 5α-androst-1-en-3-one); methylnortestosterone (17β-hydroxy-17α-methylestr- 4-en-3-one); methyltestosterone; metribolone (methyltrienolone, 17β- hydroxy-17α-methylestra-4,9,11-trien-3-one); mibolerone; nandrolone; 19- norandrostenedione (estr-4-ene-3,17-dione); norboletone; norclostebol; norethandrolone; oxabolone; oxandrolone; oxymesterone; oxymetholone; prostanozol (17β-[(tetrahydropyran-2-yl)oxy]-1'H-pyrazolo[3,4:2,3]-5α- androstane); quinbolone; stanozolol; stenbolone; 1-testosterone (17β- hydroxy-5α-androst-1-en-3-one); tetrahydrogestrinone (17-hydroxy-18a- homo-19-nor-17α-pregna-4,9,11-trien-3-one); trenbolone (17β-hydroxyestr- 4,9,11-trien-3-one); and other substances with a similar chemical structure or similar biological effect(s). b. Endogenous** AAS when administered exogenously: androstenediol (androst-5-ene-3β,17β-diol); androstenedione (androst-4-ene- 3,17-dione); dihydrotestosterone (17β-hydroxy-5α-androstan-3-one); prasterone (dehydroepiandrosterone, DHEA, 3β-hydroxyandrost-5-en-17-one); testosterone; and their metabolites and isomers, including but not limited to: 5α-androstane-3α,17α-diol; 5α-androstane-3α,17β-diol; 5α-androstane- 3β,17α-diol; 5α-androstane-3β,17β-diol; androst-4-ene-3α,17α-diol; androst-4-ene-3α,17β-diol; androst-4-ene-3β,17α-diol; androst-5-ene- 3α,17α-diol; androst-5-ene-3α,17β-diol; androst-5-ene-3β,17α-diol; 4-androstenediol (androst-4-ene-3β,17β-diol); 5-androstenedione (androst-5- ene-3,17-dione); epi-dihydrotestosterone; epitestosterone; etiocholanolone; 3α-hydroxy-5α-androstan-17-one; 3β-hydroxy-5α- androstan-17-one; 7α-hydroxy-DHEA ; 7β-hydroxy-DHEA ; 7-keto-DHEA; 19-norandrosterone; 19-noretiocholanolone. 2. Other Anabolic Agents, including but not limited to: Clenbuterol, selective androgen receptor modulators (SARMs), tibolone, zeranol, zilpaterol. The 2014 Prohibited List 11 September 2013 4 For purposes of this section: * “exogenous” refers to a substance which is not ordinarily produced by the body naturally. ** “endogenous” refers to a substance which is ordinarily produced by the body naturally. S2. PEPTIDE HORMONES, GROWTH FACTORS AND RELATED SUBSTANCES The following substances, and other substances with similar chemical structure or similar biological effect(s), are prohibited: 1. Erythropoiesis-Stimulating Agents [e.g. erythropoietin (EPO), darbepoetin (dEPO), hypoxia-inducible factor (HIF) stabilizers, methoxy polyethylene glycol-epoetin beta (CERA), peginesatide (Hematide)]; 2. Chorionic Gonadotrophin (CG) and Luteinizing Hormone (LH) and their releasing factors, in males; 3. Corticotrophins and their releasing factors; 4. Growth Hormone (GH) and its releasing factors and Insulin-like Growth Factor-1 (IGF-1). In addition, the following growth factors are prohibited Fibroblast Growth Factors (FGFs), Hepatocyte Growth Factor (HGF), Mechano Growth Factors (MGFs), Platelet-Derived Growth Factor (PDGF), Vascular-Endothelial Growth Factor (VEGF) as well as any other growth factor affecting muscle, tendon or ligament protein synthesis/degradation, vascularisation, energy utilization, regenerative capacity or fibre type switching; and other substances with similar chemical structure or similar biological effect(s). S3. BETA-2 AGONISTS All beta-2 agonists, including all optical isomers (e.g. d- and l-) where relevant, are prohibited except inhaled salbutamol (maximum 1600 micrograms over 24 hours), inhaled formoterol (maximum delivered dose 54 micrograms over 24 hours) and salmeterol when taken by inhalation in accordance with the manufacturers’ recommended therapeutic regimen. The 2014 Prohibited List 11 September 2013 5 The presence in urine of salbutamol in excess of 1000 ng/mL or formoterol in excess of 40 ng/mL is presumed not to be an intended therapeutic use of the substance and will be considered as an Adverse Analytical Finding unless the Athlete proves, through a controlled pharmacokinetic study, that the abnormal result was the consequence of the use of the therapeutic inhaled dose up to the maximum indicated above. S4. HORMONE AND METABOLIC MODULATORS The following are prohibited: 1. Aromatase inhibitors including, but not limited to: aminoglutethimide, anastrozole, androsta-1,4,6-triene-3,17-dione (androstatrienedione), 4-androstene-3,6,17 trione (6-oxo), exemestane, formestane, letrozole, testolactone. 2. Selective estrogen receptor modulators (SERMs) including, but not limited to: raloxifene, tamoxifen, toremifene. 3. Other anti-estrogenic substances including, but not limited to: clomiphene, cyclofenil, fulvestrant. 4. Agents modifying myostatin function(s) including, but not limited, to: myostatin inhibitors. 5. Metabolic modulators: a) Insulins b) Peroxisome Proliferator Activated Receptor δ (PPARδ) agonists (e.g. GW 1516), PPARδ-AMP-activated protein kinase (AMPK) axis agonists (e.g. AICAR) S5. DIURETICS AND OTHER MASKING AGENTS Masking agents are prohibited. They include: Diuretics, desmopressin, plasma expanders (e.g. glycerol; intravenous administration of albumin, dextran, hydroxyethyl starch and mannitol), probenecid; and other substances with similar biological effect(s). Local administration of felypressin in dental anaesthesia is not prohibited. Diuretics include: Acetazolamide, amiloride, bumetanide, canrenone, chlortalidone, etacrynic acid, furosemide, indapamide, metolazone, spironolactone, thiazides (e.g. bendroflumethiazide, chlorothiazide, hydrochlorothiazide), triamterene, vaptans (e.g. tolvaptan); and other substances with a similar The 2014 Prohibited List 11 September 2013 6 chemical structure or similar biological effect(s) (except drospirenone, pamabrom and topical dorzolamide and brinzolamide, which are not prohibited). The use In- and Out-of-Competition, as applicable, of any quantity of a substance subject to threshold limits (i.e. formoterol, salbutamol, cathine, ephedrine, methylephedrine and pseudoephedrine) in conjunction with a diuretic or other masking agent requires the deliverance of a specific Therapeutic Use Exemption for that substance in addition to the one granted for the diuretic or other masking agent. The 2014 Prohibited List 11 September 2013 7 PROHIBITED METHODS M1. MANIPULATION OF BLOOD AND BLOOD COMPONENTS The following are prohibited: 1. The administration or reintroduction of any quantity of autologous, allogenic (homologous) or heterologous blood or red blood cell products of any origin into the circulatory system. 2. Artificially enhancing the uptake, transport or delivery of oxygen, including, but not limited to, perfluorochemicals, efaproxiral (RSR13) and modified haemoglobin products (e.g. haemoglobin-based blood substitutes, microencapsulated haemoglobin products), excluding supplemental oxygen. 3. Any form of intravascular manipulation of the blood or blood components by physical or chemical means. M2. CHEMICAL AND PHYSICAL MANIPULATION The following are prohibited: 1. Tampering, or attempting to tamper, in order to alter the integrity and validity of Samples collected during Doping Control. These include but are not limited to urine substitution and/or adulteration (e.g. proteases). 2. Intravenous infusions and/or injections of more than 50 mL per 6 hour period except for those legitimately received in the course of hospital admissions or clinical investigations. M3. GENE DOPING The following, with the potential to enhance sport performance, are prohibited: 1. The transfer of polymers of nucleic acids or nucleic acid analogues; 2. The use of normal or genetically modified cells. The 2014 Prohibited List 11 September 2013 8 SUBSTANCES AND METHODS PROHIBITED IN-COMPETITION In addition to the categories S0 to S5 and M1 to M3 defined above, the following categories are prohibited In-Competition: PROHIBITED SUBSTANCES S6. STIMULANTS All stimulants, including all optical isomers (e.g. d- and l-) where relevant, are prohibited, except imidazole derivatives for topical use and those stimulants included in the 2014 Monitoring Program*. Stimulants include: a: Non-Specified Stimulants: Adrafinil; amfepramone; amfetamine; amfetaminil; amiphenazole; benfluorex; benzylpiperazine; bromantan; clobenzorex; cocaine; cropropamide; crotetamide; fencamine; fenetylline; fenfluramine; fenproporex; fonturacetam [4-phenylpiracetam (carphedon)]; furfenorex; mefenorex; mephentermine; mesocarb; metamfetamine(d-); p-methylamphetamine; modafinil; norfenfluramine; phendimetrazine; phenmetrazine; phentermine; prenylamine; prolintane. A stimulant not expressly listed in this section is a Specified Substance. b: Specified Stimulants (examples): Benzfetamine; cathine**; cathinone and its analogues (e.g. mephedrone, methedrone, α- pyrrolidinovalerophenone); dimethylamphetamine; ephedrine***; epinephrine**** (adrenaline); etamivan; etilamfetamine; etilefrine; famprofazone; fenbutrazate; fencamfamin; heptaminol; hydroxyamfetamine (parahydroamphetamine); isometheptene; levmetamfetamine; meclofenoxate; methylenedioxymethamphetamine; methylephedrine***; methylhexaneamine (dimethylpentylamine); methylphenidate; nikethamide; norfenefrine; octopamine; oxilofrine (methylsynephrine); pemoline; pentetrazol; phenpromethamine; propylhexedrine; pseudoephedrine*****; selegiline; sibutramine; strychnine; tenamfetamine (methylenedioxyamphetamine); trimetazidine; tuaminoheptane; and other substances with a similar chemical structure or similar biological effect(s). The 2014 Prohibited List 11 September 2013 9 * The following substances included in the 2014 Monitoring Program (bupropion, caffeine, nicotine, phenylephrine, phenylpropanolamine, pipradol, synephrine) are not considered as Prohibited Substances. ** Cathine is prohibited when its concentration in urine is greater than 5 micrograms per milliliter. *** Each of ephedrine and methylephedrine is prohibited when its concentration in urine is greater than 10 micrograms per milliliter. **** Local administration (e.g. nasal, ophthalmologic) of epinephrine (adrenaline) or co-administration with local anaesthetic agents is not prohibited. ***** Pseudoephedrine is prohibited when its concentration in urine is greater than 150 micrograms per milliliter. S7. NARCOTICS The following are prohibited: Buprenorphine, dextromoramide, diamorphine (heroin), fentanyl and its derivatives, hydromorphone, methadone, morphine, oxycodone, oxymorphone, pentazocine, pethidine. S8. CANNABINOIDS Natural (e.g. cannabis, hashish, marijuana) or synthetic delta 9- tetrahydrocannabinol (THC) and cannabimimetics (e.g. “Spice”, JWH018, JWH073, HU-210) are prohibited. S9. GLUCOCORTICOSTEROIDS All glucocorticosteroids are prohibited when administered by oral, intravenous, intramuscular or rectal routes. The 2014 Prohibited List 11 September 2013 10 SUBSTANCES PROHIBITED IN PARTICULAR SPORTS P1. ALCOHOL Alcohol (ethanol) is prohibited In-Competition only, in the following sports. Detection will be conducted by analysis of breath and/or blood. The doping violation threshold is equivalent to a blood alcohol concentration of 0.10 g/L. • Air Sports (FAI) • Archery (WA) • Automobile (FIA) • Karate (WKF) • Motorcycling (FIM) • Powerboating (UIM) P2. BETA-BLOCKERS Unless otherwise specified, beta-blockers are prohibited In-Competition only, in the following sports. • Archery (WA) (also prohibited Out-of-Competition) • Automobile (FIA) • Billiards (all disciplines) (WCBS) • Darts (WDF) • Golf (IGF) • Shooting (ISSF, IPC) (also prohibited Out-of-Competition) • Skiing/Snowboarding (FIS) in ski jumping, freestyle aerials/halfpipe and snowboard halfpipe/big air Beta-blockers include, but are not limited to, the following: Acebutolol, alprenolol, atenolol, betaxolol, bisoprolol, bunolol, carteolol, carvedilol, celiprolol, esmolol, labetalol, levobunolol, metipranolol, metoprolol, nadolol, oxprenolol, pindolol, propranolol, sotalol, timolol. THE 2014 PROHIBITED LIST SUBSTANCES AND METHODS PROHIBITED AT ALL TIMES (IN- AND OUT-OF-COMPETITION) 1. UAnabolic Androgenic Steroids (AAS) a. Exogenous* AAS, including: SUBSTANCES AND METHODS PROHIBITED IN-COMPETITION In addition to the categories S0 to S5 and M1 to M3 defined above, the following categories are prohibited In-Competition: US6. STIMULANTS US8. CANNABINOIDS US9. GLUCOCORTICOSTEROIDS All glucocorticosteroids are prohibited when administered by oral, intravenous, intramuscular or rectal routes. UP1. ALCOHOL Air Sports (FAI) Archery (WA) Automobile (FIA) Karate (WKF) Motorcycling (FIM) UP2. BETA-BLOCKERS

20 September 2014 2015 Prohibited List Summary of Major Modifications and Explanatory Notes SUBSTANCES AND METHODS PROHIBITED AT ALL TIMES (IN- AND OUT-OF- COMPETITION) PROHIBITED SUBSTANCES S1: Anabolic Agents Changes were made to reflect current scientific nomenclature. 5β-androstane-3α,17β-diol was added to the examples of testosterone metabolites. S2. Peptide Hormones, Growth Factors, Related Substances and Mimetics The title of this section has been changed: Mimetics have been added to the title to reflect the fact that synthetic analogs are also prohibited under this section. Please note that all the substances named as examples in this revised section of the 2015 Prohibited List where already considered prohibited under previous Prohibited Lists, as applicable. The ESA sub-section has been expanded by adding the non-erythropoietic EPO-Receptor agonists. In addition, the HIF stabilizer sub-section has been placed in a separate paragraph to highlight the growing importance of these drugs and to specifically identify HIF activators such as xenon and argon. Note that cyanocobalamin (vitamin B12) is not prohibited. Examples of Chorionic Gonadotrophin (CG) and Luteinizing Hormone (LH) releasing factors have now been identified. A Corticotrophin releasing factor has now been added as an example. GH releasing factors have been divided in a more precise categorization and several examples of each have been added to illustrate their different pharmacological properties. IGF-1 has been moved to the other growth factor section. Note that Platelet Derived Plasma preparations are not prohibited. S4. Hormone and Metabolic Modulators Trimetazidine was originally included in S6.b based upon the similarity of its chemical structure to some of the listed Stimulants. It has been moved to the newly created sub-section S4.5.c as it is pharmacologically classified as a modulator of cardiac metabolism. AMPK activators were re-described to reflect current nomenclature. S5. Diuretics and Masking Agents The title and subsequent paragraphs has been modified by the removal of the word “other” to reflect that diuretics are not only masking agents but can also be abused for other purposes such as notably the induction of rapid weight loss. The last paragraph has been reworded for the sake of clarity. The principle and processes identified in the previous version of the Prohibited List remain unchanged. PROHIBITED METHODS M2. Chemical and Physical Manipulation The term “surgical procedures” has been added to the sentence describing the situations in which the administration of intravenous infusions or injections of more than 50 mL per 6 hours are permitted when medically required. SUBSTANCES AND METHODS PROHIBITED IN-COMPETITION S6. Stimulants: For the sake of clarification, topical/ophthalmic imidazole derivatives have been mentioned as exceptions of non-prohibited stimulants. Phenmetrazine has been moved from section S6.a to S6.b to reflect the fact that it is metabolized into fenbutrazate, which is already listed under S6.b. The List now clearly identifies the whole family of phenethylamine derivatives as being prohibited to address the growing number of illegal, designer stimulants derived from phenethylamine. Trimetazidine has been transferred to the newly created section S4.5.c (see above). S9: Glucocorticoids: Glucocorticosteroids are described as Glucocorticoids to reflect current nomenclature and use. SUBSTANCES PROHIBITED IN PARTICULAR SPORTS P1: Alcohol: Following the request of World Karate Federation (WKF), karate was removed from the list of sports in which alcohol is prohibited P2. Beta-blockers The World Underwater Federation (CMAS) has, at its request, been added to the group of International Federations prohibiting the use of Beta-blockers in competition for certain disciplines. MONITORING PROGRAM Following sufficient collection of data leading to clear conclusions, monitoring of pseudoephedrine below 150 microgram per milliliter will cease in 2015. Telmisartan, an atypical angiotensin II receptor antagonist with apparent partial PPARδ receptor agonist properties (prohibited under S4.5.b), was added to the Monitoring Program to assess the abuse of this substance. Meldonium, a drug with potential cardiac effects, was added to the Monitoring Program to assess the abuse of this substance.

20 September 2014 2015 Prohibited List Summary of Major Modifications and Explanatory Notes SUBSTANCES AND METHODS PROHIBITED AT ALL TIMES (IN- AND OUT-OF- COMPETITION) PROHIBITED SUBSTANCES S1: Anabolic Agents Changes were made to reflect current scientific nomenclature. 5β-androstane-3α,17β-diol was added to the examples of testosterone metabolites. S2. Peptide Hormones, Growth Factors, Related Substances and Mimetics The title of this section has been changed: Mimetics have been added to the title to reflect the fact that synthetic analogs are also prohibited under this section. Please note that all the substances named as examples in this revised section of the 2015 Prohibited List where already considered prohibited under previous Prohibited Lists, as applicable. The ESA sub-section has been expanded by adding the non-erythropoietic EPO-Receptor agonists. In addition, the HIF stabilizer sub-section has been placed in a separate paragraph to highlight the growing importance of these drugs and to specifically identify HIF activators such as xenon and argon. Note that cyanocobalamin (vitamin B12) is not prohibited. Examples of Chorionic Gonadotrophin (CG) and Luteinizing Hormone (LH) releasing factors have now been identified. A Corticotrophin releasing factor has now been added as an example. GH releasing factors have been divided in a more precise categorization and several examples of each have been added to illustrate their different pharmacological properties. IGF-1 has been moved to the other growth factor section. Note that Platelet Derived Plasma preparations are not prohibited. S4. Hormone and Metabolic Modulators Trimetazidine was originally included in S6.b based upon the similarity of its chemical structure to some of the listed Stimulants. It has been moved to the newly created sub-section S4.5.c as it is pharmacologically classified as a modulator of cardiac metabolism. AMPK activators were re-described to reflect current nomenclature. S5. Diuretics and Masking Agents The title and subsequent paragraphs has been modified by the removal of the word “other” to reflect that diuretics are not only masking agents but can also be abused for other purposes such as notably the induction of rapid weight loss. The last paragraph has been reworded for the sake of clarity. The principle and processes identified in the previous version of the Prohibited List remain unchanged. PROHIBITED METHODS M2. Chemical and Physical Manipulation The term “surgical procedures” has been added to the sentence describing the situations in which the administration of intravenous infusions or injections of more than 50 mL per 6 hours are permitted when medically required. SUBSTANCES AND METHODS PROHIBITED IN-COMPETITION S6. Stimulants: For the sake of clarification, topical/ophthalmic imidazole derivatives have been mentioned as exceptions of non-prohibited stimulants. Phenmetrazine has been moved from section S6.a to S6.b to reflect the fact that it is metabolized into fenbutrazate, which is already listed under S6.b. The List now clearly identifies the whole family of phenethylamine derivatives as being prohibited to address the growing number of illegal, designer stimulants derived from phenethylamine. Trimetazidine has been transferred to the newly created section S4.5.c (see above). S9: Glucocorticoids: Glucocorticosteroids are described as Glucocorticoids to reflect current nomenclature and use. SUBSTANCES PROHIBITED IN PARTICULAR SPORTS P1: Alcohol: Following the request of World Karate Federation (WKF), karate was removed from the list of sports in which alcohol is prohibited P2. Beta-blockers The World Underwater Federation (CMAS) has, at its request, been added to the group of International Federations prohibiting the use of Beta-blockers in competition for certain disciplines. MONITORING PROGRAM Following sufficient collection of data leading to clear conclusions, monitoring of pseudoephedrine below 150 microgram per milliliter will cease in 2015. Telmisartan, an atypical angiotensin II receptor antagonist with apparent partial PPARδ receptor agonist properties (prohibited under S4.5.b), was added to the Monitoring Program to assess the abuse of this substance. Meldonium, a drug with potential cardiac effects, was added to the Monitoring Program to assess the abuse of this substance.

WORLD ANTI-DOPING CODE INTERNATIONAL STANDARD PROHIBITED LIST 2023 This List shall come into effect on 1 January 2023. www.wada-ama.org 2 SUBSTANCES & METHODS PROHIBITED AT ALL TIMES S0 Non-approved substances.........................................................................................................4 S1 Anabolic agents................................................................................................................................5 Some of these substance(s) may be found, without limitation, in medications used for the treatment of e.g. male hypogonadism. S2 Peptide hormones, growth factors, related substances, and mimetics............7 Some of these substance(s) may be found, without limitation, in medications used for the treatment of e.g. anaemia, male hypogonadism, growth hormone deficiency. S3 Beta-2 agonists.................................................................................................................................9 Some of these substance(s) may be found, without limitation, in medications used for the treatment of e.g. asthma and other respiratory disorders. S4 Hormone and metabolic modulators................................................................................... 10 Some of these substance(s) may be found, without limitation, in medications used for the treatment of e.g. breast cancer, diabetes, infertility (female), polycystic ovarian syndrome. S5 Diuretics and masking agents................................................................................................ 12 Some of these substance(s) may be found, without limitation, in medications used for the treatment of e.g. heart failure, hypertension. M1 – M2 – M3 Prohibited Methods............................................................................................. 13 SUBSTANCES & METHODS PROHIBITED IN-COMPETITION S6 Stimulants........................................................................................................................................... 14 Some of these substance(s) may be found, without limitation, in medications used for the treatment of e.g. anaphylaxis, attention deficit hyperactivity disorders (ADHD), cold and influenza symptoms. S7 Narcotics............................................................................................................................................. 16 Some of these substance(s) may be found, without limitation, in medications used for the treatment of e.g. pain, including from musculoskeletal injuries. S8 Cannabinoids.................................................................................................................................... 17 S9 Glucocorticoids............................................................................................................................... 18 Some of these substance(s) may be found, without limitation, in medications used for the treatment of e.g. allergy, anaphylaxis, asthma, inflammatory bowel disease. SUBSTANCES PROHIBITED IN PARTICULAR SPORTS P1 Beta-blockers................................................................................................................................... 19 Some of these substance(s) may be found, without limitation, in medications used for the treatment of e.g. heart failure, hypertension. INDEX................................................................................................................................................................... 20 TABLE OF CONTENTS Please note that the list of examples of medical conditions below is not inclusive. 3 Introduction The Prohibited List is a mandatory International Standard as part of the World Anti-Doping Program. The List is updated annually following an extensive consultation process facilitated by WADA. The effective date of the List is 01 January 2023. The official text of the Prohibited List shall be maintained by WADA and shall be published in English and French. In the event of any conflict between the English and French versions, the English version shall prevail. Below are some terms used in this List of Prohibited Substances and Prohibited Methods. Prohibited In-Competition Subject to a different period having been approved by WADA for a given sport, the In-Competition period shall in principle be the period commencing just before midnight (at 11:59 p.m.) on the day before a Competition in which the Athlete is scheduled to participate until the end of the Competition and the Sample collection process. Prohibited at all times This means that the substance or method is prohibited In- and Out-of-Competition as defined in the Code. Specified and non-Specified As per Article 4.2.2 of the World Anti-Doping Code, “for purposes of the application of Article 10, all Prohibited Substances shall be Specified Substances except as identified on the Prohibited List. No Prohibited Method shall be a Specified Method unless it is specifically identified as a Specified Method on the Prohibited List”. As per the comment to the article, “the Specified Substances and Methods identified in Article 4.2.2 should not in any way be considered less important or less dangerous than other doping substances or methods. Rather, they are simply substances and methods which are more likely to have been consumed or used by an Athlete for a purpose other than the enhancement of sport performance.” Substances of Abuse Pursuant to Article 4.2.3 of the Code, Substances of Abuse are substances that are identified as such because they are frequently abused in society outside of the context of sport. The following are designated Substances of Abuse: cocaine, diamorphine (heroin), methylenedioxymethamphetamine (MDMA/”ecstasy”), tetrahydrocannabinol (THC). THE 2023 PROHIBITED LIST WORLD ANTI-DOPING CODE VALID 1 JANUARY 2023 Published by: World Anti-Doping Agency Stock Exchange Tower 800 Place Victoria (Suite 1700) PO Box 120 Montreal, Quebec Canada H4Z 1B7 URL: www.wada-ama.org Tel: +1 514 904 9232 Fax: +1 514 904 8650 E-mail: code@wada-ama.org 4 S0 Any pharmacological substance which is not addressed by any of the subsequent sections of the List and with no current approval by any governmental regulatory health authority for human therapeutic use (e.g. drugs under pre-clinical or clinical development or discontinued, designer drugs, substances approved only for veterinary use) is prohibited at all times. This class covers many different substances including but not limited to BPC-157. PROHIBITED AT ALL TIMES (IN- AND OUT-OF-COMPETITION) All prohibited substances in this class are Specified Substances. NON-APPROVED SUBSTANCES 5 • 1-Androstenediol (5ɑ-androst-1-ene-3ß, 17ß-diol) • 1-Androstenedione (5ɑ-androst-1-ene-3, 17-dione) • 1-Androsterone (3ɑ-hydroxy-5a-androst-1- ene-17-one) • 1-Epiandrosterone (3ß-hydroxy-5ɑ-androst- 1-ene-17-one) • 1-Testosterone (17ß-hydroxy-5ɑ-androst-1- en-3-one) • 4-Androstenediol (androst-4-ene-3ß, 17ß-diol) • 4-Hydroxytestosterone (4,17ß-dihydroxyandrost-4-en-3-one) • 5-Androstenedione (androst-5-ene-3,17-dione) • 7ɑ-hydroxy-DHEA • 7ß-hydroxy-DHEA • 7-Keto-DHEA • 17ɑ-methylepithiostanol (epistane) • 19-Norandrostenediol (estr-4-ene-3,17-diol) • 19-Norandrostenedione (estr-4-ene-3,17-dione) • Androst-4-ene-3,11,17- trione (11-ketoandrostenedione, adrenosterone) • Androstanolone (5ɑ-dihydrotestosterone, 17ß-hydroxy-5ɑ-androstan-3-one) • Androstenediol (androst-5-ene-3ß,17ß-diol) • Androstenedione (androst-4-ene-3,17-dione) • Bolasterone • Boldenone • Boldione (androsta-1,4-diene-3,17-dione) • Calusterone • Clostebol • Danazol ([1,2]oxazolo[4’,5’:2,3]pregna-4-en- 20-yn-17ɑ-ol) • Dehydrochlormethyltestosterone (4-chloro- 17ß-hydroxy-17ɑ-methylandrosta-1,4-dien-3- one) • Desoxymethyltestosterone (17ɑ-methyl- 5ɑ-androst-2-en-17ß-ol and 17ɑ-methyl-5ɑ- androst-3-en-17ß-ol) • Drostanolone • Epiandrosterone (3ß-hydroxy-5ɑ-androstan- 17-one) • Epi-dihydrotestosterone (17ß-hydroxy-5ß- androstan-3-one) • Epitestosterone • Ethylestrenol (19-norpregna-4-en-17ɑ-ol) • Fluoxymesterone • Formebolone • Furazabol (17ɑ-methyl [1,2,5] oxadiazolo[3’,4’:2,3]-5ɑ-androstan-17ß-ol) • Gestrinone Anabolic agents are prohibited. When administered exogenously, including but not limited to: 1. ANABOLIC ANDROGENIC STEROIDS (AAS) S1 ANABOLIC AGENTS PROHIBITED AT ALL TIMES (IN- AND OUT-OF-COMPETITION) All prohibited substances in this class are non-Specified Substances. 6 S1 • Mestanolone • Mesterolone • Metandienone (17ß-hydroxy-17ɑ- methylandrosta-1,4-dien-3-one) • Metenolone • Methandriol • Methasterone (17ß-hydroxy-2ɑ,17ɑ-dimethyl- 5ɑ-androstan-3-one) • Methyl-1-testosterone (17ß-hydroxy-17ɑ- methyl-5ɑ-androst-1-en-3-one) • Methylclostebol • Methyldienolone (17ß-hydroxy-17ɑ- methylestra-4,9-dien-3-one) • Methylnortestosterone (17ß-hydroxy-17ɑ- methylestr-4-en-3-one) • Methyltestosterone • Metribolone (methyltrienolone, 17ß-hydroxy- 17ɑ-methylestra-4,9,11-trien-3-one) • Mibolerone • Nandrolone (19-nortestosterone) • Norboletone • Norclostebol (4-chloro-17ß-ol-estr-4-en-3-one) • Norethandrolone • Oxabolone • Oxandrolone • Oxymesterone • Oxymetholone • Prasterone (dehydroepiandrosterone, DHEA, 3ß-hydroxyandrost-5-en-17-one) • Prostanozol (17ß-[(tetrahydropyran-2-yl)oxy]- 1’H-pyrazolo[3,4:2,3]-5ɑ-androstane) • Quinbolone • Stanozolol • Stenbolone • Testosterone • Tetrahydrogestrinone (17-hydroxy-18a- homo-19-nor-17ɑ-pregna-4,9,11-trien-3-one) • Tibolone • Trenbolone (17ß-hydroxyestr-4,9,11-trien-3- one) and other substances with a similar chemical structure or similar biological effect(s). 1. ANABOLIC ANDROGENIC STEROIDS (AAS) (continued) 2. OTHER ANABOLIC AGENTS Including, but not limited to: Clenbuterol, osilodrostat, ractopamine, selective androgen receptor modulators [SARMs, e.g. andarine, enobosarm (ostarine), LGD-4033 (ligandrol), RAD140, S-23 and YK-11], zeranol and zilpaterol. ANABOLIC AGENTS (continued) 7 S2 Including, but not limited to: 1.1 Erythropoietin receptor agonists, e.g. darbepoetins (dEPO); erythropoietins (EPO); EPO-based constructs [e.g. EPO-Fc, methoxy polyethylene glycol-epoetin beta (CERA)]; EPO-mimetic agents and their constructs (e.g. CNTO-530, peginesatide). 1.2 Hypoxia-inducible factor (HIF) activating agents, e.g. cobalt; daprodustat (GSK1278863); IOX2; molidustat (BAY 85-3934); roxadustat (FG-4592); vadadustat (AKB-6548); xenon. 1.3 GATA inhibitors, e.g. K-11706. 1.4 Transforming growth factor beta (TGF-ß) signalling inhibitors, e.g. luspatercept; sotatercept. 1.5 Innate repair receptor agonists, e.g. asialo EPO; carbamylated EPO (CEPO). The following substances, and other substances with similar chemical structure or similar biological effect(s), are prohibited. 1. ERYTHROPOIETINS (EPO) AND AGENTS AFFECTING ERYTHROPOIESIS PEPTIDE HORMONES, GROWTH FACTORS, RELATED SUBSTANCES, AND MIMETICS PROHIBITED AT ALL TIMES (IN- AND OUT-OF-COMPETITION) All prohibited substances in this class are non-Specified Substances. 8 Including, but not limited to: • Fibroblast growth factors (FGFs) • Hepatocyte growth factor (HGF) • Insulin-like growth factor 1 (IGF-1) and its analogues • Mechano growth factors (MGFs) • Platelet-derived growth factor (PDGF) • Thymosin-ß4 and its derivatives e.g. TB-500 • Vascular endothelial growth factor (VEGF) and other growth factors or growth factor modulators affecting muscle, tendon or ligament protein synthesis/degradation, vascularisation, energy utilization, regenerative capacity or fibre type switching. 3. GROWTH FACTORS AND GROWTH FACTOR MODULATORS S2 PEPTIDE HORMONES, GROWTH FACTORS, RELATED SUBSTANCES, AND MIMETICS (continued) 2.1 Chorionic gonadotrophin (CG) and luteinizing hormone (LH) and their releasing factors in males, e.g. buserelin, deslorelin, gonadorelin, goserelin, leuprorelin, nafarelin and triptorelin 2.2 Corticotrophins and their releasing factors, e.g. corticorelin 2.3 Growth hormone (GH), its analogues and fragments including, but not limited to: • growth hormone analogues, e.g. lonapegsomatropin, somapacitan and somatrogon • growth hormone fragments, e.g. AOD-9604 and hGH 176-191 2.4 Growth hormone releasing factors, including, but not limited to: • growth hormone-releasing hormone (GHRH) and its analogues (e.g. CJC-1293, CJC-1295, sermorelin and tesamorelin) • growth hormone secretagogues (GHS) and their mimetics [e.g. lenomorelin (ghrelin), anamorelin, ipamorelin, macimorelin and tabimorelin] • GH-releasing peptides (GHRPs) [e.g. alexamorelin, GHRP-1, GHRP-2 (pralmorelin), GHRP-3, GHRP-4, GHRP-5, GHRP-6, and examorelin (hexarelin)] 2. PEPTIDE HORMONES AND THEIR RELEASING FACTORS 9 S3 PROHIBITED AT ALL TIMES (IN- AND OUT-OF-COMPETITION) All prohibited substances in this class are Specified Substances. All selective and non-selective beta-2 agonists, including all optical isomers, are prohibited. Including, but not limited to: • Arformoterol • Fenoterol • Formoterol • Higenamine • Indacaterol • Levosalbutamol • Olodaterol • Procaterol • Reproterol • Salbutamol • Salmeterol • Terbutaline • Tretoquinol (trimetoquinol) • Tulobuterol • Vilanterol The presence in urine of salbutamol in excess of 1000 ng/mL or formoterol in excess of 40 ng/mL is not consistent with therapeutic use of the substance and will be considered as an Adverse Analytical Finding (AAF) unless the Athlete proves, through a controlled pharmacokinetic study, that the abnormal result was the consequence of a therapeutic dose (by inhalation) up to the maximum dose indicated above. NOTE • Inhaled salbutamol: maximum 1600 micrograms over 24 hours in divided doses not to exceed 600 micrograms over 8 hours starting from any dose; • Inhaled formoterol: maximum delivered dose of 54 micrograms over 24 hours; • Inhaled salmeterol: maximum 200 micrograms over 24 hours; • Inhaled vilanterol: maximum 25 micrograms over 24 hours. EXCEPTIONS BETA-2 AGONISTS 10 S4 The following hormone and metabolic modulators are prohibited. Including, but not limited to: • 2-Androstenol (5ɑ-androst-2-en-17-ol) • 2-Androstenone (5ɑ-androst-2-en-17-one) • 3-Androstenol (5ɑ-androst-3-en-17-ol) • 3-Androstenone (5ɑ-androst-3-en-17-one) • 4-Androstene-3,6,17 trione (6-oxo) • Aminoglutethimide • Anastrozole • Androsta-1,4,6-triene-3,17-dione (androstatrienedione) • Androsta-3,5-diene-7,17-dione (arimistane) • Exemestane • Formestane • Letrozole • Testolactone 4.1. AROMATASE INHIBITORS Including, but not limited to: • Bazedoxifene • Clomifene • Cyclofenil • Fulvestrant • Ospemifene • Raloxifene • Tamoxifen • Toremifene 4.2. ANTI-ESTROGENIC SUBSTANCES [ANTI-ESTROGENS AND SELECTIVE ESTROGEN RECEPTOR MODULATORS (SERMS)] PROHIBITED AT ALL TIMES (IN- AND OUT-OF-COMPETITION) Prohibited substances in classes S4.1 and S4.2 are Specified Substances. Those in classes S4.3 and S4.4 are non-Specified Substances. HORMONE AND METABOLIC MODULATORS 11 Including, but not limited to: • Activin A-neutralizing antibodies • Activin receptor IIB competitors such as: – Decoy activin receptors (e.g. ACE-031) • Anti-activin receptor IIB antibodies (e.g. bimagrumab) • Myostatin inhibitors such as: – Agents reducing or ablating myostatin expression – Myostatin-binding proteins (e.g. follistatin, myostatin propeptide) – Myostatin- or precursor-neutralizing antibodies (e.g. apitegromab, domagro- zumab, landogrozumab, stamulumab) 4.3. AGENTS PREVENTING ACTIVIN RECEPTOR IIB ACTIVATION 4.4.1 Activators of the AMP-activated protein kinase (AMPK), e.g. AICAR, SR9009; and peroxisome proliferator-activated receptor delta (PPARδ) agonists, e.g. 2-(2-methyl-4-((4-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)methylthio) phenoxy) acetic acid (GW1516, GW501516) 4.4.2 Insulins and insulin-mimetics 4.4.3 Meldonium 4.4.4 Trimetazidine 4.4. METABOLIC MODULATORS S4 HORMONE AND METABOLIC MODULATORS (continued) 12 S5 PROHIBITED AT ALL TIMES (IN- AND OUT-OF-COMPETITION) All prohibited substances in this class are Specified Substances. All diuretics and masking agents, including all optical isomers, e.g. d- and l- where relevant, are prohibited. Including, but not limited to: • Desmopressin; probenecid; plasma expanders, e.g. intravenous administration of albumin, dextran, hydroxyethyl starch and mannitol. • Acetazolamide; amiloride; bumetanide; canrenone; chlortalidone; etacrynic acid; furosemide; indapamide; metolazone; spironolactone; thiazides, e.g. bendroflumethiazide, chlorothiazide and hydrochlorothiazide; torasemide; triamterene and vaptans, e.g. tolvaptan. and other substances with a similar chemical structure or similar biological effect(s). DIURETICS AND MASKING AGENTS The detection in an Athlete’s Sample at all times or In-Competition, as applicable, of any quantity of the following substances subject to threshold limits: formoterol, salbutamol, cathine, ephedrine, methylephedrine and pseudoephedrine, in conjunction with a diuretic or masking agent (except topical ophthalmic administration of a carbonic anhydrase inhibitor or local administration of felypressin in dental anaesthesia), will be considered as an Adverse Analytical Finding (AAF) unless the Athlete has an approved Therapeutic Use Exemption (TUE) for that substance in addition to the one granted for the diuretic or masking agent. NOTE • Drospirenone; pamabrom; and topical ophthalmic administration of carbonic anhydrase inhibitors (e.g. dorzolamide, brinzolamide); • Local administration of felypressin in dental anaesthesia. EXCEPTIONS 13 PROHIBITED METHODS The following are prohibited: 1. The Administration or reintroduction of any quantity of autologous, allogenic (homologous) or heterologous blood, or red blood cell products of any origin into the circulatory system. 2. Artificially enhancing the uptake, transport or delivery of oxygen. Including, but not limited to: Perfluorochemicals; efaproxiral (RSR13); voxelotor and modified haemoglobin products, e.g. haemoglobin-based blood substitutes and microencapsulated haemoglobin products, excluding supplemental oxygen by inhalation. 3. Any form of intravascular manipulation of the blood or blood components by physical or chemical means. M1. MANIPULATION OF BLOOD AND BLOOD COMPONENTS The following are prohibited: 1. Tampering, or Attempting to Tamper, to alter the integrity and validity of Samples collected during Doping Control. Including, but not limited to: Sample substitution and/or adulteration, e.g. addition of proteases to Sample. 2. Intravenous infusions and/or injections of more than a total of 100 mL per 12-hour period except for those legitimately received in the course of hospital treatments, surgical procedures or clinical diagnostic investigations. M2. CHEMICAL AND PHYSICAL MANIPULATION The following, with the potential to enhance sport performance, are prohibited: 1. The use of nucleic acids or nucleic acid analogues that may alter genome sequences and/or alter gene expression by any mechanism. This includes but is not limited to gene editing, gene silencing and gene transfer technologies. 2. The use of normal or genetically modified cells. M3. GENE AND CELL DOPING PROHIBITED AT ALL TIMES (IN- AND OUT-OF-COMPETITION) All prohibited methods in this class are non-Specified except methods in M2.2. which are Specified Methods. 14 S6 All stimulants, including all optical isomers, e.g. d- and l- where relevant, are prohibited. A stimulant not expressly listed in this section is a Specified Substance. PROHIBITED IN-COMPETITION All prohibited substances in this class are Specified Substances except those in S6.A, which are non-Specified Substances. Substances of Abuse in this section: cocaine and methylenedioxymethamphetamine (MDMA / “ecstasy”) Stimulants include: • Adrafinil • Amfepramone • Amfetamine • Amfetaminil • Amiphenazole • Benfluorex • Benzylpiperazine • Bromantan • Clobenzorex • Cocaine • Cropropamide • Crotetamide • Fencamine • Fenetylline • Fenfluramine • Fenproporex • Fonturacetam [4-phenylpiracetam (carphedon)] • Furfenorex • Lisdexamfetamine • Mefenorex • Mephentermine • Mesocarb • Metamfetamine(d-) • p-methylamfetamine • Modafinil • Norfenfluramine • Phendimetrazine • Phentermine • Prenylamine • Prolintane A: NON-SPECIFIED STIMULANTS STIMULANTS 15 S6 Including, but not limited to: • 3-Methylhexan-2-amine (1,2-dimethylpentylamine) • 4-fluoromethylphenidate • 4-Methylhexan-2-amine (methylhexaneamine, 1,3-dimethylamylamine, 1,3 DMAA) • 4-Methylpentan-2-amine (1,3-dimethylbutylamine) • 5-Methylhexan-2-amine (1,4-dimethylpentylamine, 1,4-dimethylamylamine, 1,4-DMAA) • Benzfetamine • Cathine** • Cathinone and its ana- logues, e.g. mephedrone, methedrone, and ɑ - pyrrolidinovalerophenone • Dimetamfetamine (dimethylamphetamine) • Ephedrine*** • Epinephrine**** (adrenaline) • Etamivan • Ethylphenidate • Etilamfetamine • Etilefrine • Famprofazone • Fenbutrazate • Fencamfamin • Heptaminol • Hydrafinil (fluorenol) • Hydroxyamfetamine (parahydroxyamphet- amine) • Isometheptene • Levmetamfetamine • Meclofenoxate • Methylenedioxymetham- phetamine • Methylephedrine*** • Methylnaphthidate [((±)-methyl-2-(naphthalen-2- yl)-2-(piperidin-2-yl)acetate] • Methylphenidate • Nikethamide • Norfenefrine • Octodrine (1,5-dimethyl- hexylamine) • Octopamine • Oxilofrine (methylsynephrine) • Pemoline • Pentetrazol • Phenethylamine and its derivatives • Phenmetrazine • Phenpromethamine • Propylhexedrine • Pseudoephedrine***** • Selegiline • Sibutramine • Solriamfetol • Strychnine • Tenamfetamine (methylenedioxyamphet- amine) • Tuaminoheptane * Bupropion, caffeine, nicotine, phenylephrine, phenylpropanolamine, pipradrol, and synephrine: These substances are included in the 2023 Monitoring Program and are not considered Prohibited Substances. ** Cathine (d-norpseudoephedrine) and its l-isomer: Prohibited when its concentration in urine is greater than 5 micrograms per millilitre. *** Ephedrine and methylephedrine: Prohibited when the concentration of either in urine is greater than 10 micrograms per millilitre. **** Epinephrine (adrenaline): Not prohibited in local administration, e.g. nasal, ophthalmologic, or co-administration with local anaesthetic agents. ***** Pseudoephedrine: Prohibited when its concentration in urine is greater than 150 micrograms per millilitre. B: SPECIFIED STIMULANTS • Clonidine; • Imidazoline derivatives for dermatological, nasal, ophthalmic or otic use (e.g. brimonidine, clonazoline, fenoxazoline, indanazoline, naphazoline, oxymetazoline, tetryzoline, xylometazoline) and those stimulants included in the 2023 Monitoring Program*. and other substances with a similar chemical structure or similar biological effect(s). STIMULANTS (continued) EXCEPTIONS 16 S7 • Buprenorphine • Dextromoramide • Diamorphine (heroin) • Fentanyl and its derivatives • Hydromorphone • Methadone • Morphine • Nicomorphine • Oxycodone • Oxymorphone • Pentazocine • Pethidine The following narcotics, including all optical isomers, e.g. d- and l- where relevant, are prohibited. PROHIBITED IN-COMPETITION All prohibited substances in this class are Specified Substances. Substance of Abuse in this section: diamorphine (heroin) NARCOTICS 17 S8 All natural and synthetic cannabinoids are prohibited, e.g. • In cannabis (hashish, marijuana) and cannabis products • Natural and synthetic tetrahydrocannabinols (THCs) • Synthetic cannabinoids that mimic the effects of THC PROHIBITED IN-COMPETITION All prohibited substances in this class are Specified Substances. Substance of Abuse in this section: tetrahydrocannabinol (THC) • Cannabidiol CANNABINOIDS EXCEPTIONS 18 S9 All glucocorticoids are prohibited when administered by any injectable, oral [including oromucosal (e.g. buccal, gingival, sublingual)] or rectal route. Including, but not limited to: • Beclometasone • Betamethasone • Budesonide • Ciclesonide • Cortisone • Deflazacort • Dexamethasone • Fluocortolone • Flunisolide • Fluticasone • Hydrocortisone • Methylprednisolone • Mometasone • Prednisolone • Prednisone • Triamcinolone acetonide PROHIBITED IN-COMPETITION All prohibited substances in this class are Specified Substances. GLUCOCORTICOIDS • Other routes of administration (including inhaled, and topical: dental-intracanal, dermal, intranasal, ophthalmological, otic and perianal) are not prohibited when used within the manufacturer’s licensed doses and therapeutic indications. NOTE 19 P1 Beta-blockers are prohibited In-Competition only, in the following sports, and also prohibited Out-of-Competition where indicated (*). • Archery (WA)* • Automobile (FIA) • Billiards (all disciplines) (WCBS) • Darts (WDF) • Golf (IGF) • Mini-Golf (WMF) • Shooting (ISSF, IPC)* • Skiing/Snowboarding (FIS) in ski jumping, freestyle aerials/halfpipe and snowboard halfpipe/big air • Underwater sports (CMAS)* in all subdisciplines of freediving, spearfishing and target shooting Including, but not limited to: • Acebutolol • Alprenolol • Atenolol • Betaxolol • Bisoprolol • Bunolol • Carteolol • Carvedilol • Celiprolol • Esmolol • Labetalol • Metipranolol • Metoprolol • Nadolol • Nebivolol • Oxprenolol • Pindolol • Propranolol • Sotalol • Timolol *Also prohibited Out-of-Competition PROHIBITED IN PARTICULAR SPORTS All prohibited substances in this class are Specified Substances. BETA-BLOCKERS 20 INDEX (±)-Methyl-2-(naphthalen-2-yl)-2- (piperidin-2-yl)acetate, 15 1-Androstenediol, 5 1-Androstenedione, 5 1-Androsterone, 5 1-Epiandrosterone, 5 1-Testosterone, 5 1,2-Dimethylpentylamine, 15 [1,2]Oxazolo[4’,5’:2,3]pregna-4-en-20- yn-17ɑ-ol), 5 1,3-Dimethylamylamine (1,3 DMAA), 15 1,3-Dimethylbutylamine, 15 1,4-Dimethylamylamine (1,4-DMAA), 15 1,4-Dimethylpentylamine, 15 1,5- Dimethyl-hexylamine, 15 2-Androstenol, 10 2-Androstenone, 10 3ɑ-Hydroxy-5ɑ-androst-1-ene-17-one, 5 3ß-Hydroxy-5ɑ-androst-1-ene-17-one, 5 3ß-Hydroxy-5ɑ-androstan-17-one, 5 3ß-Hydroxyandrost-5-en-17-one, 6 3-Androstenol, 10 3-Androstenone, 10 3-Methylhexan-2-amine, 15 4-Androstene-3,6,17 trione, 10 4-Androstenediol, 5 4-Chloro-17ß-hydroxy-17ɑ- methylandrosta-1,4-dien-3-one, 5 4-Chloro-17ß-ol-estr-4-en-3-one, 6 4-Fluoromethylphenidate, 15 4-Hydroxytestosterone, 5 4-Methylhexan-2-amine, 15 4-Methylpentan-2-amine, 15 4-Phenylpiracetam, 14 4,17ß-Dihydroxyandrost-4-en-3-one, 5 5ɑ-Androst-1-ene-3, 17-dione, 5 5ɑ-Androst-1-ene-3ß, 17ß-diol, 5 5ɑ-Androst-2-en-17-ol, 10 5ɑ-Androst-2-en-17-one, 10 5ɑ-Androst-3-en-17-ol, 10 5ɑ-Androst-3-en-17-one, 10 5ɑ-Dihydrotestosterone, 5 5-Androstenedione, 5 5-Methylhexan-2-amine, 15 6-Oxo, 10 7ɑ-Hydroxy-DHEA, 5 7ß-Hydroxy-DHEA, 5 7-Keto-DHEA, 5 11-Ketoandrostenedione, 5 17ɑ-Methyl [1,2,5]oxadiazolo[3’,4’:2,3]- 5ɑ-androstan-17ß-ol, 5 17ɑ-Methyl-5ɑ-androst-2-en-17ß-ol, 5 17ɑ-Methyl-5ɑ-androst-3-en-17ß-ol, 5 17ɑ-Methylepithiostanol, 5 17ß-Hydroxy-2ɑ,17ɑ-dimethyl-5ɑ- androstan-3-one, 6 17ß-Hydroxy-5ɑ-androst-1-en-3-one, 5 17ß-Hydroxy-5ɑ-androstan-3-one, 5 17ß-Hydroxy-5ß-androstan-3-one, 5 17ß-hydroxy-17ɑ-methyl-5ɑ-androst-1- en-3-one, 6 17ß-Hydroxy-17ɑ-methylandrosta-1,4- dien-3-one, 6 17ß-Hydroxy-17ɑ-methylestr-4-en-3- one, 6 17ß-Hydroxy-17ɑ-methylestra-4,9-dien- 3-one, 6 17ß-Hydroxy-17ɑ-methylestra-4,9,11- trien-3-one, 6 17ß-Hydroxyestr-4,9,11-trien-3-one, 6 17ß-[(Tetrahydropyran-2-yl)oxy]-1’H- pyrazolo[3,4:2,3]-5ɑ-androstane, 6 17-Hydroxy-18a-homo-19-nor-17ɑ- pregna-4,9,11-trien-3-one, 6 19-Norandrostenediol, 5 19-Norandrostenedione, 5 19-Norpregna-4-en-17ɑ-ol, 5 19-Nortestosterone, 6 ɑ-Pyrrolidinovalerophenone, 15 A ACE-031, 11 Acebutolol, 19 Acetazolamide, 12 Activin A-neutralizing antibodies, 11 Activin receptor IIB competitors, 11 Adrafinil, 14 Adrenaline, 15 Adrenosterone, 5 AICAR, 11 Albumin, 12 Alexamorelin, 8 Alprenolol, 19 Amfepramone, 14 Amfetamine, 14 Amfetaminil, 14 Amiloride, 12 Aminoglutethimide, 10 Amiphenazole, 14 AMP-activated protein kinase (AMPK), 11 Anamorelin, 8 Anastrozole, 10 Andarine, 6 Androst-4-ene-3ß,17ß-diol, 5 Androst-4-ene-3,11,17- trione, 5 Androst-4-ene-3,17-dione, 5 Androst-5-ene-3ß,17ß-diol, 5 Androst-5-ene-3,17-dione, 5 Androsta-1,4,6-triene-3,17-dione, 10 Androsta-1,4-diene-3,17-dione, 5 Androsta-3,5-diene-7,17-dione, 10 Androstanolone, 5 Androstatrienedione, 10 Androstenediol, 5 Androstenedione, 5 Anti-activin receptor IIB antibodies, 11 AOD-9604, 7 Apitegromab, 11 Arformoterol, 9 Arimistane, 10 Asialo EPO, 7 Atenolol, 19 B Bazedoxifene, 10 Beclometasone, 18 Bendroflumethiazide, 12 Benfluorex, 14 Benzfetamine, 15 Benzylpiperazine, 14 Betamethasone, 18 Betaxolol, 19 Bimagrumab, 11 Bisoprolol, 19 Blood, 13 Blood (autologous), 13 Blood (components), 13 Blood (heterologous), 13 Blood (homologous), 13 Blood manipulation, 13 Bolasterone, 5 Boldenone, 5 Boldione, 5 BPC-157, 4 Brimonidine, 15 Brinzolamide, 12 21 INDEX Bromantan, 14 Budesonide, 18 Bumetanide, 12 Bunolol, 19 Buprenorphine, 16 Buserelin, 8 C Calusterone, 5 Cannabidiol, 17 Cannabis, 17 Canrenone, 12 Carbamylated EPO (CEPO), 7 Carphedon, 14 Carteolol, 19 Carvedilol, 19 Cathine, 12, 15 Cathinone, 15 Celiprolol, 19 Cell (doping), 13 Cell (genetically modified), 13 Cell (normal), 13 Cell (red blood), 13 Chlorothiazide, 12 Chlortalidone, 12 Chorionic Gonadotrophin (CG), 8 Ciclesonide, 18 CJC-1293, 8 CJC-1295, 8 Clenbuterol, 6 Clobenzorex, 14 Clomifene, 10 Clonazoline, 15 Clonidine, 15 Clostebol, 5 CNTO-530, 7 Cobalt, 7 Cocaine, 14 Corticorelin, 8 Corticotrophins, 8 Cortisone, 18 Cropropamide, 14 Crotetamide, 14 Cyclofenil, 10 D Danazol, 5 Daprodustat, 7 Darbepoetins (dEPO), 7 Deflazacort, 18 Dehydrochlormethyltestosterone, 5 Dehydroepiandrosterone (DHEA), 6 Deslorelin, 8 Desmopressin, 12 Desoxymethyltestosterone, 5 Dexamethasone, 18 Dextran, 12 Dextromoramide, 16 Diamorphine, 16 Dimetamfetamine, 15 Dimethylamphetamine, 15 Domagrozumab, 11 Dorzolamide, 12 Drospirenone, 12 Drostanolone, 5 E Ecstasy, 14 Efaproxiral (RSR13), 13 Enobosarm, 6 Ephedrine, 12, 15 Epiandrosterone, 5 Epi-dihydrotestosterone, 5 Epinephrine, 15 Epistane, 5 Epitestosterone, 5 EPO-based constructs, 7 EPO-Fc, 7 EPO-mimetic agents, 7 Erythropoietin receptor agonists, 7 Erythropoietins (EPO), 7 Esmolol, 19 Estr-4-ene-3,17-diol, 5 Estr-4-ene-3,17-dione, 5 Etacrynic acid, 12 Etamivan, 15 Ethylestrenol, 5 Ethylphenidate, 15 Etilamfetamine, 15 Etilefrine, 15 Examorelin, 8 Exemestane, 10 F Famprofazone, 15 Felypressin, 12 Fenbutrazate, 15 Fencamfamin, 15 Fencamine, 14 Fenetylline, 14 Fenfluramine, 14 Fenoterol, 9 Fenoxazoline, 15 Fenproporex, 14 Fentanyl, 16 Fibroblast growth factors (FGFs), 8 Flunisolide, 18 Fluocortolone, 18 Fluorenol, 15 Fluoxymesterone, 5 Fluticasone, 18 Follistatin, 11 Fonturacetam, 14 Formebolone, 5 Formestane, 10 Formoterol, 9, 12 Fulvestrant, 10 Furazabol, 5 Furfenorex, 14 Furosemide, 12 G GATA inhibitors, 7 Gene doping, 13 Gene editing, 13 Gene silencing, 13 Gene transfer, 13 Gestrinone, 5 Ghrelin, 8 GH-releasing peptides (GHRPs), 8 Gonadorelin, 8 Goserelin, 8 Growth hormone (GH), 8 Growth hormone secretagogues (GHS), 8 GW1516, 11 GW501516, 11 H Haemoglobin (products), 13 Haemoglobin (based blood substitutes), 13 Haemoglobin (microencapsulated products), 13 Hashish, 17 22 INDEX Hepatocyte growth factor (HGF), 8 Heptaminol, 15 Heroin, 16 Hexarelin, 8 hGH 176-191, 8 Higenamine, 9 Hydrafinil, 15 Hydrochlorothiazide, 12 Hydrocortisone, 18 Hydromorphone, 16 Hydroxyamfetamine, 15 Hydroxyethyl starch, 12 Hypoxia-inducible factor (HIF) activating agents, 7 I Imidazoline, 15 Indacaterol, 9 Indanazoline, 15 Indapamide, 12 Infusions, 13 Injections (> 100 mL), 13 Innate repair receptor agonists, 7 Insulin-like growth factor-1 (IGF-1), 8 Insulin-mimetics, 11 Insulins, 11 Intravenous infusions/injections, 13 IOX2, 7 Ipamorelin, 8 Isometheptene, 15 K K-11706, 7 L Labetalol, 19 Landogrozumab, 11 Lenomorelin, 8 Letrozole, 10 Leuprorelin, 8 Levmetamfetamine, 15 Levosalbutamol, 9 LGD-4033, 6 Ligandrol, 6 Lisdexamfetamine, 14 Lonapegsomatropin, 8 Luspatercept, 7 Luteinizing hormone (LH), 8 M Macimorelin, 8 Mannitol, 12 Marijuana, 17 Mechano growth factors (MGFs), 8 Meclofenoxate, 15 Mefenorex, 14 Meldonium, 11 Mephedrone, 15 Mephentermine, 14 Mesocarb, 14 Mestanolone, 6 Mesterolone, 6 Metamfetamine(d-), 14 Metandienone, 6 Metenolone, 6 Methadone, 16 Methandriol, 6 Methasterone, 6 Methedrone, 15 Methoxy polyethylene glycol-epoetin beta (CERA), 7 Methyl-1-testosterone, 6 Methylclostebol, 6 Methyldienolone, 6 Methylenedioxyamphetamine, 15 Methylenedioxymethamphetamine, 15 Methylephedrine, 12, 15 Methylhexaneamine, 15 Methylnaphtidate, 15 Methylnortestosterone, 6 Methylphenidate, 15 Methylprednisolone, 18 Methylsynephrine, 15 Methyltestosterone, 6 Methyltrienolone, 6 Metipranolol, 19 Metolazone, 12 Metoprolol, 19 Metribolone, 6 Mibolerone, 6 Modafinil, 14 Molidustat, 7 Mometasone, 18 Morphine, 16 Myostatin inhibitors, 11 Myostatin precursor-neutralizing antibodies, 11 Myostatin propeptide, 11 Myostatin-binding proteins, 11 Myostatin-neutralizing antibodies, 11 N Nadolol, 19 Nafarelin, 8 Nandrolone, 6 Naphazoline, 15 Nebivolol, 19 Nicomorphine, 16 Nikethamide, 15 Norboletone, 6 Norclostebol, 6 Norethandrolone, 6 Norfenefrine, 15 Norfenfluramine, 14 Nucleic acids, 13 Nucleic acid analogues, 13 O Octodrine, 15 Octopamine, 15 Olodaterol, 9 Osilodrostat, 6 Ospemifene, 10 Ostarine, 6 Oxabolone, 6 Oxandrolone, 6 Oxilofrine, 15 Oxprenolol, 19 Oxycodone, 16 Oxymesterone, 6 Oxymetazoline, 15 Oxymetholone, 6 Oxymorphone, 16 P Pamabrom, 12 Parahydroxyamphetamine, 15 Peginesatide, 7 Pemoline, 15 Pentazocine, 16 Pentetrazol, 15 Perfluorochemicals, 13 Peroxisome proliferator activated receptor delta agonists, 11 Pethidine, 16 Phendimetrazine, 14 Phenethylamine, 15 23 INDEX Phenmetrazine, 15 Phenpromethamine, 15 Phentermine, 14 Pindolol, 19 Plasma expanders, 12 Platelet-derived growth factor (PDGF), 8 p-methylamfetamine, 14 Pralmorelin, 8 Prasterone, 6 Prednisolone, 18 Prednisone, 18 Prenylamine, 14 Probenecid, 12 Procaterol, 9 Prolintane, 14 Propranolol, 19 Propylhexedrine, 15 Prostanozol, 6 Proteases, 13 Pseudoephedrine, 12, 15 Q Quinbolone, 6 R RAD140, 6 Ractopamine, 6 Raloxifene, 10 Reproterol, 9 Roxadustat, 7 S S-23, 6 Salbutamol, 9, 12 Salmeterol, 9 Selective androgen receptor modulators (SARMs), 6 Selegiline, 15 Sermorelin, 8 Sibutramine, 15 Solriamfetol, 15 Somapacitan, 8 Somatrogon, 8 Sotalol, 19 Sotatercept, 7 Spironolactone, 12 SR9009, 11 Stamulumab, 11 Stanozolol, 6 Stenbolone, 6 Strychnine, 15 T Tabimorelin, 8 Tamoxifen, 10 Tampering, 13 TB-500, 8 Tenamfetamine, 15 Terbutaline, 9 Tesamorelin, 8 Testolactone, 10 Testosterone, 6 Tetrahydrocannabinols, 17 Tetrahydrogestrinone, 6 Tetryzoline, 15 Thiazides, 12 Thymosin-ß4, 8 Tibolone, 6 Timolol, 19 Tolvaptan, 12 Torasemide, 12 Toremifene, 10 Transforming growth factor beta (TGF-ß) signalling inhibitors, 7 Trenbolone, 6 Tretoquinol, 9 Triamcinolone acetonide, 18 Triamterene, 12 Trimetazidine, 11 Trimetoquinol, 9 Triptorelin, 8 Tuaminoheptane, 15 Tulobuterol, 9 V Vadadustat (AKB-6548), 7 Vaptans, 12 Vascular endothelial growth factor (VEGF), 8 Vilanterol, 9 Voxelotor, 13 X Xenon, 7 Xylometazoline, 15 Y YK-11, 6 Z Zeranol, 6 Zilpaterol, 6 www.wada-ama.org www.wada-ama.org www.wada-ama.org www.wada-ama.org www.wada-ama.org www.wada-ama.org