ts of the recent technical documents from the World Anti-Doping Agency (WADA) considering their minimum required performance levels (MRPL) are fulfilled, and the method was validated for its utilisation [...] initial testing procedure in doping controls. Finally, the approach was applied to authentic post-administration study urine samples (for insulins and gonadorelin) in order to provide proof of principle.

documents (TD2022 MRPL) for doping controls. The proof of principle was shown by the analysis of post administration samples after treatment with synthetic insulin analogues.

analytes from complex sample matrices such as blood and urine when spotted onto a paper strip. By minimizing sample preparation and omitting chromatographic separation, paper spray mass spectrometry benefits [...] compounds fulfilled the World Anti-Doping Agency's (WADA's) requirements regarding the applicable minimum required performance limits for initial testing procedures. In addition, the combination of paper

Schänzer,W. Emerging Drugs - Potential for misuse in sport and doping control detection strategies. Mini-Reviews in Medicinal Chemistry 2007, 7, (5), 533-539. Thevis, M.; Kamber, M.; Schänzer,W.: Screening for

Edelhäuser vom Ministerium ländlicher Raum Stuttgart über Untersuchungen von 138 Nahrungsergänzungsstoffen des deutschen und internationalen Marktes, wobei 16 Produkte mit kontaminierten Steroidhormonen

Dvorak J: Traditional Chinese Medicine and Sports Drug Testing: Identification of Natural Steroid Administration in Doping Control Urine Samples Resulting from Musk (Pod) Extracts. Br J Sports Med. 2013 Ja

Organ on a chip - doping analysis Mit Mini-Organen dem Doping auf der Spur siehe Artikel DSHS-Köln "Mit Mini-Organen dem Doping auf der Spur" Publikation Görgens C, Ramme AP, Guddat S,et al. Organ-on-a-chip [...] profile was in agreement with phase-I and phase-II biotransformation products regularly seen in postadministration urine specimens. In conclusion, this pilot study indicates that the “organ-on-a-chip” technology [...] technology provides a high degree of conformity with traditional human oral administration studies, providing a promising approach for metabolic profiling in sports drug testing. Paper -Download Paper - DSHS

bekommen. Da Methyltrienolon sehr stark an den Androgenrezeptor bindet, kaum an Plasmaproteine und nur minimal metabolisiert wird (1), wird die Substanz häufig in wissenschaftlichen Studien zur Charakterisierung

Donike tried to improve the detection of AAS, even for long periods of time after their last administration. download complete presentation

Thevis M: Detection of myo-inositol trispyrophosphate (ITPP) in human urine following an oral administration of ITPP – a pilot study. In: Thevis M, Geyer H, Mareck U (eds.) Recent advances in doping analysis [...] Loganathan D, Morrissey B. Detection of myo-inositol tris pyrophosphate (ITPP) in equine following an administration of ITPP. Drug Test Anal. 2014 Mar;6(3):268-76. Abstract Abb.2 Chemische Strukturformel von ITTP