c means for the treatment of numerous diseases but can also be relevant as performance-enhancing agents in sports. Areas covered: Within this review, classical and emerging protein-therapeutics with (presumed) [...] novel/improved biomarkers indicative of protein doping. Keywords: Doping; erythropoiesis-stimulating agents (ESAs); fusion protein; growth hormone; inhibitors of the activin receptor signaling pathways (IASPs);

PMC12144231. Sternberg J, Peters I, Naumann N, Thomas A, Thevis M. In Vitro Metabolism of Doping Agents (Stanozolol, LGD-4033, Anastrozole, GW1516, Trimetazidine) by Human Seminal Vesicle and Liver Fractions [...] spot sample preparation enables the detection of lower molecular mass peptide and non-peptide doping agents by means of LC-HRMS. Anal Bioanal Chem. 2020; 412(15): 3765–3777. Mareck U, Fusshöller G, Geyer H [...] M, Thevis M. An in vitro assay approach to investigate the potential impact of different doping agents on the steroid profile.Drug Test Anal. 2021 May;13(5):916-928. doi: 10.1002/dta.2991. Epub 2020 Dec

ppen publiziert: A. Breidbach, D. H. Catlin. RSR13, a potential athletic performance enhancement agent: Detection in urine by gas chromatography/mass spectrometry. Rapid Commun. Mass Spectrom. 2001, 15

glycol-epoetin beta (CERA)]; EPO-mimetic agents and their constructs (e.g. CNTO-530, peginesatide, pegmolesatide). 1.2 Hypoxia-inducible factor (HIF) activating agents, e.g. cobalt; daprodustat (GSK1278863); [...] chemical structure or similar biological effect(s), are prohibited: 1. Erythropoietins (EPO) and agents affecting erythropoiesis, including, but not limited to: 1.1 Erythropoietin receptor agonists, e

to: Bazedoxifene; Clomifene; Cyclofenil; Fulvestrant; Ospemifene; Raloxifene; Tamoxifen; Toremifene Agents preventing activin receptor IIB activation including, but not limited, to: Activin A-neutralizing [...] ACE-031); Anti-activin receptor IIB antibodies (e.g. Bimagrumab); Myostatin inhibitors such as: Agents reducing or ablating myostatin expression; Myostatin-binding proteins (e.g. Follistatin, myostatin

Anti-Doping Agency) - Prohibited List 1st January 2024 S5 Diuretics and masking agents All diuretics and masking agents, including all optical isomers, e.g. d- and l- where relevant, are prohibited. Including

in local administration, e.g. nasal, ophthalmologic, or co-administration with local anaesthetic agents. ***** Pseudoephedrine: Prohibited when its concentration in urine is greater than 150 micrograms

3390/molecules28145541. PMID: 37513414; PMCID: PMC10385812. download article Abstract Among anabolic agents, selective androgen receptor modulators (SARMs) represent a new class of potential drugs that can [...] e mode of action. Besides possible medical applications, SARMs are used as performance-enhancing agents in sports. Therefore, they are prohibited by the World Anti-Doping Agency (WADA) in and out of c

(Thevis et al. 2009). WADA Prohibited List (January 2021) S1 ANABOLIC AGENTS 1. Anabolic Androgenic Steroids (AAS) 2. Other Aanabolic Agents Including, but not limited to: Clenbuterol, selective androgen receptor

Georgas E, Geyer H, Thevis M. Investigations into the Concentrations and Metabolite Profiles of Doping Agents and Antidepressants in Human Seminal Fluid Using Liquid Chromatography-Mass Spectrometry. Drug Metab [...] concentration ranges and metabolite profiles of therapeutic drugs that are also classified as doping agents. Therefore, a screening procedure was developed using liquid chromatography connected to a triple [...] the seminal fluid. This study demonstrated that various drugs including those categorized as doping agents partition into seminal fluid. Monitoring substances and metabolites may contribute to a better u